Directions:Preventative: 3 times daily for 3 days. Acute: Initial dose: 5 times daily for 10-15 days. Thereafter, use 3 times daily for seven days. Repeat annually or when needed. Dogs under 20 lbs: 1 pinch onto tongue. Dogs 20-50 lbs: 2 pinches onto tongue. Dogs over 50 lbs: 3 pinches onto tongue