Bimeda Inc Division Of Crosvetpharm Drugs

• Plasma-lyte 148
  

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  Plasma-lyte 148

  

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  DOSAGE AND ADMINISTRATION: The recommended dose of flunixin meglumine is 0.5 mg per lb of body weight once daily. The Flunazine® Equine Paste syringe, calibrated in twelve 250-lb weight increments, delivers 125 mg of flunixin for each 250 lbs (see dosage table). One syringe will treat a 1000-lb horse once daily for 3 days, or three 1000-lb horses one time.

  DOSAGE TABLE

   Syringe Mark*  Horse Weight (lbs)  Flunazine® Equine Paste Delevered (g) mg Flunixin Delivered   0  ---  ---  ---  250  250  2.5  125  500  500  5.0  250  750  750  7.5  375  1000  1000  10.0  500

  * Use dial edge nearest syringe barrel to mark dose.

  The paste is orally administered by inserting the nozzle of the syringe through the interdental space, and depositing the required amount of paste on the back of the tongue by depressing the plunger.

  Treatment may be given initially by intravenous or intramuscular injection of Flunazine Injectable Solution, followed by Flunazine® Equine Paste on Days 2 to 5. Flunixin meglumine treatment should not exceed 5 consecutive days.

  TOXICITY: No toxic effects were observed in rats given oral flunixin meglumine 2 mg/kg per day for 42 days. Higher doses produced ulceration of the gastrointestinal tract. The emetic dose in dogs is between 150 and 250 mg/kg. Flunixin was well tolerated in monkeys dosed daily with 4 mg/kg for 56 days. No adverse effects occurred in horses dosed orally with 1.0 or 1.5 mg/lb for 5 consecutive days.

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