Nautilus Neurosciences, Inc.

Nautilus Neurosciences, Inc. Drugs

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  2.1 Acute Treatment of Migraine

        Administer one packet (50 mg) of CAMBIA™  for the acute treatment of migraine. Empty the contents of one packet into a cup containing 1 to 2 ounces (30 to 60 mL) of water, mix well and drink immediately. Do not use liquids other than water.

        Taking CAMBIA with food may cause a reduction in effectiveness compared to taking CAMBIA on an empty stomach [see Clinical Pharmacology (12.3)].

        Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals.  The safety and effectiveness of a second dose have not been established.

  2.2 Interchangeability With Other Formulations of Diclofenac

        Different formulations of oral diclofenac (e.g., CAMBIA, diclofenac sodium enteric-coated tablets, diclofenac sodium extended-release tablets, or diclofenac potassium immediate-release tablets) may not be bioequivalent even if the milligram strength is the same. Therefore, it is not possible to convert dosing from any other formulation of diclofenac to CAMBIA.

       

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