The dose of zolpidem tartrate tablets should be individualized.
The recommended dose for adults is 10 mg immediately before bedtime.
2.2 Special populations
Elderly or debilitated patients may be especially sensitive to the effects of zolpidem tartrate tablets. Patients with hepatic insufficiency do not clear the drug as rapidly as normals. An initial 5 mg dose is recommended in these patients [seeWarnings and Precautions (5)].
2.3 Administration with CNS depressants
Downward dosage adjustment may be necessary when zolpidem tartrate tablets are administered with agents having known CNS-depressant effects because of the potentially additive effects [seeWarnings and Precautions (5)].
2.4 Maximum daily dose
The total zolpidem tartrate tablet dose should not exceed 10 mg per day.