2.1 Dosage in adults
The dose of zolpidem tartrate tablets should be individualized.
The recommended dose for adults is 10 mg immediately before bedtime.
2.2 Special Populations
Elderly or debilitated patients may be especially sensitive to the effects of zolpidem tartrate tablets . Patients with hepatic insufficiency do not clear the drug as rapidly as normals. An initial 5 mg dose is recommended in these patients [see Warnings and Precautions (5)].
2.3 Administration with CNS depressants:
Downward dosage adjustment may be necessary when zolpidem tartrate tablets is administered with agents having known CNS-depressant effects because of the potentially additive effects [see Warnings and Precautions (5)].
2.4 Maximum daily dose:
The total zolpidem tartrate tablets dose should not exceed 10 mg per day.