Guerbet Llc

Manufacturer Details

There are currently no manufacturer details available.

Share This Page

Guerbet Llc Drugs

Oxilan
Oxilan
There is currently no dosage information available for this product. We apologize for any inconvenience.
Hexabrix
Hexabrix
It is advisable that HEXABRIX be at or close to body temperature when injected.
The patient should be instructed to omit the meal that precedes the examination. Appropriate premedication, which may include a barbiturate, tranquilizer or analgesic drug, may be administered prior to the examination.
A preliminary film is recommended to check the position of the patient and the x-ray exposure factors prior to the injection of the contrast medium.
If during administration a minor reaction occurs the injection should be slowed or stopped until the reaction has subsided. If a major reaction occurs the injection should be discontinued immediately.
Under no circumstances should other drugs be administered concomitantly in the same syringe or IV administration set because of a potential for chemical incompatibility.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration.
Lipiodol
Lipiodol
2.1 Dosing Guidelines
Draw Lipiodol into a glass syringe. Use the smallest possible amount of Lipiodol according to the anatomical area to be visualized.
Hysterosalpingography
Using aseptic technique inject Lipiodol into the endometrial cavity with fluoroscopic control. Inject increments of 2 mL of Lipiodol until tubal patency is determined; stop the injection if patient develops excessive discomfort. Re-image after 24 hours to establish whether Lipiodol has entered the peritoneal cavity.
Before using Lipiodol exclude the presence of these conditions: pregnancy, uterine bleeding and endocervicitis, acute pelvic inflammatory disease, the immediate pre-or postmenstrual phase or within 30 days of curettage or conization.
Lymphography
Inject Lipiodol into a lymphatic vessel under radiologic guidance to prevent inadvertent venous administration or intravasation.
Adults:
unilateral lymphography of the upper extremities 2 to 4 mL unilateral lymphography of the lower extremities 6 to 8 mL penile lymphography 2 to 3 mL cervical lymphography 1 to 2 mL
Pediatric patients:
Inject a minimum of 1 mL to a maximum of 6 mL according to the anatomical area to be visualized. Do not exceed 0.25 mL/kg.
The following method is recommended for lymphography of the upper or lower extremities. Start the injection of Lipiodol into a lymphatic channel at a rate not to exceed 0.2 mL per minute. Inject the total dose of Lipiodol in no less than 1.25 hours. Use frequent radiologic monitoring to determine the appropriate injection rate and to follow the progress of Lipiodol within the lymphatics. Interrupt the injection if the patient experiences pain. Terminate the injection if lymphatic blockage is present to minimize introduction of Lipiodol into the venous circulation via lymphovenous channels. Terminate the injection as soon as Lipiodol is radiographically evident in the thoracic duct to minimize entry of Lipiodol into the subclavian vein and pulmonary embolization. Obtain immediate post-injection images. Re-image at 24 or 48 hours to evaluate nodal architecture.
Selective Hepatic Intra-arterial Injection
Determine the dose depending on the tumor size, local blood flow in the liver and in the tumor(s).
Inject from 1.5 to 15 mL slowly under continuous radiologic monitoring. Stop the injection when stagnation or reflux is evident. Limit the dose to only the quantity required for adequate visualization. The total dose of Lipiodol administered should not exceed 20 mL.
2.2 Drug Handling
Inspect Lipiodol visually for particulate matter and discoloration before administration. Do not use the solution if particulate matter is present or if the container appears damaged. Lipiodol is a clear, pale yellow to amber colored oil; do not use if the color has darkened.
Draw Lipiodol into a glass syringe and use promptly. Discard any unused portion of Lipiodol.
Dotarem
Dotarem
2.1 Dosing Guidelines
For adult and pediatric patients (2 years and older), the recommended dose of DOTAREM is 0.2 mL/kg (0.1 mmol/kg) body weight administered as an intravenous bolus injection, manually or by power injector, at a flow rate of approximately 2 mL/second for adults and 1 - 2 mL/second for pediatric patients. Table 1 provides weight-adjusted dose volumes.
Table 1: Volumes of DOTAREM Injection by Body Weight
Body Weight
Volume
Pounds (lb)
Kilograms (kg)
Milliliters (mL)
22
10
2
44
20
4
66
30
6
88
40
8
110
50
10
132
60
12
154
70
14
176
80
16
198
90
18
220
100
20
242
110
22
264
120
24
268
130
26
308
140
28
330
150
30
To ensure complete injection of DOTAREM the injection may be followed by normal saline flush. Contrast MRI can begin immediately following DOTAREM injection.
2.2 Drug Handling
Visually inspect DOTAREM for particulate matter prior to administration. Do not use the solution if particulate matter is present or if the container appears damaged. DOTAREM should be a clear, colorless to yellow solution. Do not mix with other drugs or parenteral nutrition. Discard any unused portions of the drug.
When DOTAREM is to be injected using plastic disposable syringes, the contrast medium should be drawn into the syringe and used immediately.
Pharmacy Bulk Package Preparation:
The Pharmacy Bulk Package is not for use in direct intravenous infusion. The transfer of DOTAREM from the Pharmacy Bulk Package should be performed in an aseptic work area, such as laminar flow hood and using aseptic technique and suitable transfer device. The closure shall be penetrated only one time. Once the container closure is punctured, the Pharmacy Bulk Package should not be removed from the aseptic work area. The Pharmacy bulk Package is used as a multiple dose container with an appropriate transfer device for filling empty sterile syringes. Each individual dose of DOTAREM should be promptly used following withdrawal from the Pharmacy Bulk Package. The contents of the Pharmacy Bulk Package should be used within 24 hours after initial puncture.
Dotarem
Dotarem
2.1 Dosing Guidelines
For adult and pediatric patients (2 years and older), the recommended dose of DOTAREM is 0.2 mL/kg (0.1 mmol/kg) body weight administered as an intravenous bolus injection, manually or by power injector, at a flow rate of approximately 2 mL/second for adults and 1 - 2 mL/second for pediatric patients. Table 1 provides weight-adjusted dose volumes.
Table 1: Volumes of DOTAREM Injection by Body Weight
Body Weight
Volume
Pounds (lb)
Kilograms (kg)
Milliliters (mL)
22
10
2
44
20
4
66
30
6
88
40
8
110
50
10
132
60
12
154
70
14
176
80
16
198
90
18
220
100
20
242
110
22
264
120
24
268
130
26
308
140
28
330
150
30
To ensure complete injection of DOTAREM the injection may be followed by normal saline flush. Contrast MRI can begin immediately following DOTAREM injection.
2.2 Drug Handling
Visually inspect DOTAREM for particulate matter prior to administration. Do not use the solution if particulate matter is present or if the container appears damaged. DOTAREM should be a clear, colorless to yellow solution. Do not mix with other drugs or parenteral nutrition. Discard any unused portions of the drug.
When DOTAREM is to be injected using plastic disposable syringes, the contrast medium should be drawn into the syringe and used immediately.