Bimeda Inc.,animal Health, Division Of Cross Vetpharm Group

---

DOSAGE AND ADMINISTRATION:

For arthritis or mycoplasma pneumonia - 5 mg/lb body weight intramuscularly once daily for three to seven days as needed.  One mL per 60 lb body weight will provide 5 mg/lb.

For optimal results, initiate treatment as soon as possible.  As with any multi-dose vial, practice aseptic techniques in withdrawing each dose.  Adequately clean and disinfect the vial closure prior to entry with a sterile needle and syringe.  No vial closure should be entered more that 20 times.

Each mL contains:

Lincomycin hydrochloride equivalent to lincomycin 300mg; also benzyl alcohol 9.45 mg added as a preservative.

---

DOSAGE AND TREATMENT:

Exodus® Multi-Dose Paste (pyrantel pamoate) is to be administered as a single oral dose of 3 mg pyrantel base per pound of body weight. The syringe has eight weight mark increments. Each weight mark indicates the recommended dose for 300 pounds of body weight. One-half syringe treats a 1200 lb horse.

DOSAGE   Body Weight Range Quantity   mg Pyrantel Base  up to 300 lb  1/8 syringe  900 mg  301 to 600 lb  1/4 syringe  1800 mg  601 to 900 lb  3/8 syringe  2700 mg  901 to 1200 lb  1/2 syringe  3600 mg

NOTE: Position ring-gauge over appropriate mark on plunger. Each mL contains 171 mg pyrantel base as pyrantel pamoate.

For maximum control of parasitism, it is recommended that foals (2-8 months of age) be dosed every 4 weeks. To minimize the potential source of infection that the mare may pose to the foal, the mare should be treated 1 month prior to anticipated foaling date followed by re-treatment 10 days to 2 weeks after birth of foal. Horses and ponies over 8 months of age should be routinely dosed every 6 weeks.

It is recommended that severely debilitated animals not be treated with this preparation.

ADMINISTRATION: After removing the cap, the paste should be deposited on the dorsum of the tongue. Introduce the nozzle end of the syringe at the corner of the mouth. Direct the syringe backwards and depress the plunger to deposit the paste onto the tongue. Given in this manner, it is unlikely that rejection of the paste will occur. Raising the horse's head sometimes assists in the swallowing process. When only part of the paste has been used, replace the cap on the syringe nozzle.

EFFICACY: Critical (worm count) studies in horses demonstrated that pyrantel pamoate administered at the recommended dosage was efficacious against mature infections of Strongylus vulgaris (>90%), S. edentatus (69%), S. equinus (>90%), Oxyuris equi (81%), Parascaris equorum (>90%), and small strongyles (>90%).