Enzon Pharmaceuticals, Inc.
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Enzon Pharmaceuticals, Inc. Drugs
2.1 Recommended Dose
The recommended dose of Oncaspar® is 2,500 IU/m2 intramuscularly (IM) or intravenously (IV). Oncaspar® should be administered no more frequently than every 14 days.
2.2 Instructions for Administration
When Oncaspar® is administered IM, the volume at a single injection site should be limited to 2 mL. If the volume to be administered is greater than 2 mL, multiple injection sites should be used.
When administered IV, Oncaspar® should be given over a period of 1 to 2 hours in 100 mL of sodium chloride or dextrose injection 5%, through an infusion that is already running.
2.3 Preparation and Handling Precautions
Do not administer Oncaspar® if drug has been:frozen stored at room temperature (+15°C to +25°C; 59°F to 77°F) for more than 48 hours shaken or vigorously agitated [see How Supplied/Storage and Handling (16)]
Parenteral drug products should be inspected visually for particulate matter, cloudiness, or discoloration prior to administration, whenever solution and container permit. If any of these are present, discard the vial.
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