Fdah, Division Of Wyeth

Fdah, Division Of Wyeth Drugs

• Centrine
  

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  Centrine

  

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  CENTRINE (aminopentamide hydrogen sulfate) may be administered by subcutaneous or intramuscular injection or by oral tablets according to the following schedule. If the desired effect is not obtained, the dosage may be gradually increased up to a maximum of 5 times the doses listed. When the condition has been brought under control by parenteral medication, treatment can be continued, if desired, with 0.2 mg scored tablets according to the dosage schedule.

  Weight of Animal Amount to be Administered Every 8 to 12 hours Dosage Injectable Volume Oral Tablets 10 lbs or less 0.1 mg 0.2 mL 1/2 Tab 11 lbs to 20 lbs 0.2 mg 0.4 mL 1 Tab 21 lbs to 50 lbs 0.3 mg 0.6 mL 1 1/2 Tabs 51 lbs to 100 lbs 0.4 mg 0.8 mL 2 Tabs Over 100 lbs 0.5 mg 1.0 mL 2 1/2 Tabs

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• Ketaset
  

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  Ketaset

  

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  KETASET is well tolerated by cats and subhuman primates when administered by intramuscular injection.

  Fasting prior to induction of anesthesia or restraint with KETASET is not essential; however, when preparing for elective surgery, it is advisable to withhold food for at least six hours prior to administration of KETASET.

  Anesthesia may be of shorter duration in immature cats. Restraint in subhuman primate neonates (less than 24 hours of age) is difficult to achieve.

  As with other anesthetic agents, the individual response to KETASET is somewhat varied depending upon the dose, general condition and age of the subject so that dosage recommendations cannot be absolutely fixed.

  Dosage

  Cats

  A dose of 11 mg/kg (5 mg/lb) is recommended to produce restraint. Dosages from 22 to 33 mg/kg (10 to 15 mg/lb) produce anesthesia that is suitable for diagnostic or minor surgical procedures that do not require skeletal muscle relaxation.

  Subhuman Primates

  The recommended restraint dosages of KETASET for the following species are: Cercocebus torquatus (white-collared mangabey), Papio cynocephalus (yellow baboon), Pantroglodytes verus (chimpanzee), Papio anubis (olive baboon), Pongo pygmaeus (orangutan), Macaca nemestrina (pigtailed macaque) 5 to 7.5 mg/kg; Presbytis entellus (entellus langur) 3 to 5 mg/kg; Gorilla gorilla gorilla (gorilla) 7 to 10 mg/kg; Aotus trivirgatus (night monkey) 10 to 12 mg/kg; Macaca mulatta (rhesus monkey) 5 to 10 mg/kg; Cebus capucinus (white-throated capuchin) 13 to 15 mg/kg; and Macaca fascicularis (crab-eating macaque), Macaca radiata (bonnet macaque) and Saimiri sciureus (squirrel monkey) 12 to 15 mg/kg.

  A single intramuscular injection produces restraint suitable for TB testing; radiography, physical examination or blood collection.

  Dosage

  Cats

  A dose of 11 mg/kg (5 mg/lb) is recommended to produce restraint. Dosages from 22 to 33 mg/kg (10 to 15 mg/lb) produce anesthesia that is suitable for diagnostic or minor surgical procedures that do not require skeletal muscle relaxation.

  Subhuman Primates

  The recommended restraint dosages of KETASET for the following species are: Cercocebus torquatus (white-collared mangabey), Papio cynocephalus (yellow baboon), Pantroglodytes verus (chimpanzee), Papio anubis (olive baboon), Pongo pygmaeus (orangutan), Macaca nemestrina (pigtailed macaque) 5 to 7.5 mg/kg; Presbytis entellus (entellus langur) 3 to 5 mg/kg; Gorilla gorilla gorilla (gorilla) 7 to 10 mg/kg; Aotus trivirgatus (night monkey) 10 to 12 mg/kg; Macaca mulatta (rhesus monkey) 5 to 10 mg/kg; Cebus capucinus (white-throated capuchin) 13 to 15 mg/kg; and Macaca fascicularis (crab-eating macaque), Macaca radiata (bonnet macaque) and Saimiri sciureus (squirrel monkey) 12 to 15 mg/kg.

  A single intramuscular injection produces restraint suitable for TB testing; radiography, physical examination or blood collection.

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