The usual initial dose of GUNA®-DIUR is:Adults and children 12 years and older 20 drops in a little water, 2 times per dayChildren between 12 years and 6 years of age 10 drops in a little water, 2 times per dayChildren under 6 years 5 drops in a glass of water, 2 times per dayFor an average of two months. If response is not satisfactory, add other products as suggested by your health care professional.