Adults and Children 2 to 12 Years of Age
The usual dosage for adults and for children weighing at least 15 kg is 2.5 mg of albuterol (one unit dose vial) administered three to four times daily by nebulization. Children weighing less than 15 kg who require less than 2.5 mg/dose (i.e., less than a full unit dose vial) should use Albuterol Sulfate Inhalation Solution, 0.5% instead of Albuterol Sulfate Inhalation Solution, 0.083%. More frequent administration or higher doses are not recommended. To administer 2.5 mg of albuterol, administer the entire contents of one sterile unit dose vial (3 mL of 0.083% inhalation solution) by nebulization. The flow rate is regulated to suit the particular nebulizer so that Albuterol Sulfate Inhalation Solution will be delivered over approximately 5 to 15 minutes.
The use of Albuterol Sulfate Inhalation Solution can be continued as medically indicated to control recurring bouts of bronchospasm. During this time most patients gain optimal benefit from regular use of the inhalation solution.
If a previously effective dosage regimen fails to provide the usual relief, medical advice should be sought immediately as this is often a sign of seriously worsening asthma that would require reassessment of therapy.
Drug compatibility (physical and chemical), efficacy, and safety of Albuterol Sulfate Inhalation Solution when mixed with other drugs in a nebulizer have not been established.
Microbial Contamination
To avoid microbial contamination, the entire contents of the unit-dose vial should be administered immediately after the vial has been opened for the first time. The nebulizer should be cleaned in accordance with the manufacturer's instructions. Failure to do so could lead to bacterial contamination of the nebulizer and possible infection.