Lyne Laboratories, Inc.

Lyne Laboratories, Inc. Drugs

• Clindamycin Palmitate H...
  

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  Clindamycin Palmitate Hydrochloride

  

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  If significant diarrhea occurs during therapy, this antibiotic should be discontinued (see WARNING box).

  Concomitant administration of food does not adversely affect the absorption of clindamycin palmitate HCl contained in clindamycin palmitate hydrochloride for oral solution (Pediatric) flavored granules.

  Serious infections: 8 to 12 mg/kg/day (4 to 6 mg/lb/day) divided into 3 or 4 equal doses.

  Severe infections: 13 to 16 mg/kg/day (6.5 to 8 mg/lb/day) divided into 3 or 4 equal doses.

  More severe infections: 17 to 25 mg/kg/day (8.5 to 12.5 mg/lb/day) divided into 3 or 4 equal doses.

  In pediatric patients weighing 10 kg or less, ½ teaspoon (37.5 mg) three times a day should be considered the minimum recommended dose.

  Serious infections due to anaerobic bacteria are usually treated with clindamycin injection. However, in clinically appropriate circumstances, the physician may elect to initiate treatment or continue treatment with clindamycin palmitate hydrochloride for oral solution (Pediatric).

  NOTE: In cases of β-hemolytic streptococcal infections, treatment should be continued for at least 10 days.

  Reconstitution Instructions: When reconstituted with water as follows, each 5 mL (teaspoonful) of solution contains clindamycin palmitate HCl equivalent to 75 mg clindamycin.

  Reconstitute bottles of 100 mL with 75 mL of water. Add a large portion of the water and shake vigorously; add the remainder of the water and shake until the solution is uniform.

  Storage Conditions: Store at 20° to 25°C (68° to 77°F)[See USP Controlled Room Temperature].

  Do NOT refrigerate the reconstituted solution; when chilled, the solution may thicken and be difficult to pour. The solution is stable for 2 weeks at room temperature.

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