The recommended dose of OraVerse is based on the number of cartridges of local anesthetic with vasoconstrictor administered:
Amount of Local Anesthetic Administered
Dose of OraVerse [mg]
Dose of OraVerse [Cartridge]
OraVerse should be administered following the dental procedure using the same location(s) and technique(s) (infiltration or block injection) employed for the administration of the local anesthetic.
Note: Do not administer OraVerse if the product is discolored or contains particulate matter.
2.2 Dosing in Special Populations
In pediatric patients weighing 15-30 kg, the maximum dose of OraVerse recommended is 1/2 cartridge (0.2 mg).
(Note: Use in pediatric patients under 6 years of age or weighing less than 15 kg (33 lbs) is not recommended. A dose of more than 1 cartridge [0.4 mg] of OraVerse has not been studied in children less than 12 years of age.)