Pharma Romlev Inc.

Pharma Romlev Inc. Drugs

• Cefditoren Pivoxil
  

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  Cefditoren Pivoxil

  

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  (See INDICATIONS AND USAGE for Indicated Pathogens.)

  Cefditoren Pivoxil Dosage and Administration* Adults and Adolescents (≥12 Years)

  Type of Infection

  Dosage

  Duration (Days)

  Community-Acquired Pneumonia

  400 mg BID

  14

  Acute Bacterial Exacerbation of Chronic Bronchitis

  400 mg BID

  10

  Pharyngitis/Tonsillitis

  200mg BID

  Uncomplicated Skin and Skin Structure Infections

  *Should be taken with meals

  Patients with Renal Insufficiency

  No dose adjustment is necessary for patients with mild renal impairment (CLcr: 50-80 mL/min/1.73 m2). It is recommended that not more than 200 mg BID be administered to patients with moderate renal impairment (CLcr: 30-49 mL/min/1.73 m2) and 200 mg QD be administered to patients with severe renal impairment (CLcr: <30 mL/min/1.73 m2). The appropriate dose in patients with end-stage renal disease has not been determined.

  Patients with Hepatic Disease

  No dose adjustments are necessary for patients with mild or moderate hepatic impairment (Child-Pugh Class A or B). The pharmacokinetics of cefditoren have not been studied in patients with severe hepatic impairment (Child-Pugh Class C).

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