Pharma Romlev Inc.
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Pharma Romlev Inc. Drugs
(See INDICATIONS AND USAGE for Indicated Pathogens.)
Cefditoren Pivoxil Dosage and Administration* Adults and Adolescents (≥12 Years)
Type of Infection
400 mg BID
Acute Bacterial Exacerbation of Chronic Bronchitis
400 mg BID
Uncomplicated Skin and Skin Structure Infections
*Should be taken with meals
Patients with Renal Insufficiency
No dose adjustment is necessary for patients with mild renal impairment (CLcr: 50-80 mL/min/1.73 m2). It is recommended that not more than 200 mg BID be administered to patients with moderate renal impairment (CLcr: 30-49 mL/min/1.73 m2) and 200 mg QD be administered to patients with severe renal impairment (CLcr: <30 mL/min/1.73 m2). The appropriate dose in patients with end-stage renal disease has not been determined.
Patients with Hepatic Disease
No dose adjustments are necessary for patients with mild or moderate hepatic impairment (Child-Pugh Class A or B). The pharmacokinetics of cefditoren have not been studied in patients with severe hepatic impairment (Child-Pugh Class C).
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