Rockwell Medical, Inc

Rockwell Medical, Inc Drugs

• Triferic
  

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  Triferic

  

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  2.1 Recommended Dose

  Inspect Triferic ampules for signs of precipitation prior to mixing with the bicarbonate concentrate. Triferic ampules appear slightly yellow-green in color.

  Triferic should only be added to the bicarbonate concentrate and should NOT be added to acid concentrate mixtures.

  Add Triferic to bicarbonate concentrate used for generation of hemodialysate. The final concentration of Triferic iron (III) in the final hemodialysate is 2 micromolar (110 mcg/L). Add one Triferic ampule to 2.5 gallons (9.46 L) of bicarbonate concentrate for preparation of the hemodialysate with 2 micromolar (110 mcg/L) iron (III) final concentration. Multiple ampules can be added to the master bicarbonate mix at each center at a ratio of one (1) ampule to each 2.5 gallons of bicarbonate concentrate.

  Triferic 50 mL multiple dose ampules can be added to each 25 gallons of master bicarbonate mix at each center at a ratio of one (1) ampule for each 25 gallons of bicarbonate concentrate.

  Administer Triferic to patients at each dialysis procedure for as long as patients are receiving maintenance hemodialysis therapy for CKD.

  The dosage of Triferic® is expressed as mg of iron (III). Each mL of Triferic contains 5.44 mg of iron as iron (III).

  Hemodialysis solutions should be used within 24 hours of the preparation of the Triferic/bicarbonate concentrate mixture.

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