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• Phenylbutazone
  

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  Phenylbutazone

  

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  DOSAGE-DOGS:

  ORALLY

  20 mg per pound body weight (100 mg/5 lbs.) daily in 3 divided doses, not to exceed 800 mg daily regardless of body weight. 

  DOSAGE-HORSES:

  ORALLY 1-2 grams per 500 lbs. body weight, not to exceed 4 grams daily. 

  ADMINISTRATION:

  1. Use a relatively high dose for the first 48 hours, then reduce gradually to a maintenance dose.  Maintain lowest dose capable of producing the desired clinical response.

  2. In many cases tablets may be crushed and given with feed. Reduce the dosage as symptoms regress.  In some cases treatment may be given only when symptoms appear with no need for continuous medication. 

  3. In animals, phenylbutazone is largely metabolized in 8 hours.  It is recommended that a third of the daily dose be administered at 8 hour intervals. 

  4. Many chronic conditions will respond to phenylbutazone therapy but discontinuance of treatment may result in the recurrence of symptoms. 

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