Shake well. Wet coat thoroughly before applying shampoo. Work shampoo into coat until a lather is produced. Allow to stand 10-15 minutes and then rinse thoroughly. Repeat if necessary. Micro-Pearls Advantage™ Seba-Moist™ Antiseborrheic Shampoo may be used 2-3 times weekly as an initial therapy, then at required intervals. As with any medicated shampoo, gloves should be worn when applying product.