There is currently no warning information available for this product. We apologize for any inconvenience.
There is currently no manufacturer warning information available for this drug.
There is currently no usage information available for this product. We apologize for any inconvenience.
Inhalation Anesthetic For Use in Dogs
Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Petrem® (sevoflurane, USP), a volatile liquid, is a halogenated general inhalation anesthetic drug. Its chemical name is fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether, and its structural formula is:
Sevoflurane Physical Constants are:
Molecular weight 200.05
Boiling point at 760 mm Hg 58.6°C
Specific gravity at 20°C 1.520-1.525 g/mL
Vapor pressure in mm Hg at 20°C 157
at 25°C 197
at 36°C 317
Distribution Partition Coefficients at 37°C:
Blood/Gas 0.63-0.69
Water/Gas 0.36
Olive Oil/Gas 47-54
Brain/Gas 1.15
Mean Component/Gas Partition Coefficients at 25°C for Polymers Used Commonly in Medical Applications:
Conductive rubber 14.0
Butyl rubber 7.7
Polyvinyl chloride 17.4
Polyethylene 1.3
Sevoflurane is nonflammable and nonexplosive as defined by the requirements of International Electrotechnical Commission 601-2-13.
Sevoflurane is a clear, colorless, stable liquid containing no additives or chemical stabilizers. Sevoflurane is nonpungent. It is miscible with ethanol, ether, chloroform and petroleum benzene, and it is slightly soluble in water. Sevoflurane is stable when stored under normal room lighting condition according to instructions.