Aspirin And Dipyridamole
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Questions & Answers
Side Effects & Adverse Reactions
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Legal Issues
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FDA Safety Alerts
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Manufacturer Warnings
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FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Aspirin and extended-release dipyridamole capsules are indicated to reduce the risk of stroke in patients who have had transient ischemia of the brain or completed ischemic stroke due to thrombosis.
History
There is currently no drug history available for this drug.
Other Information
Aspirin and extended-release dipyridamole capsules are a combination antiplatelet agent intended for oral administration. Each hard gelatin capsule contains 200 mg dipyridamole in an extended-release form and 25 mg aspirin, as an immediate-release sugar-coated tablet. In addition, each capsule contains the following inactive ingredients: acacia, aluminum stearate, colloidal silicon dioxide, corn starch, dimethicone, hypromellose, hypromellose phthalate, lactose monohydrate, methacrylic acid copolymer, microcrystalline cellulose, povidone, stearic acid, sucrose, talc, tartaric acid, titanium dioxide and triacetin.
Each capsule shell contains gelatin, red iron oxide and yellow iron oxide, titanium dioxide and water.
Dipyridamole
Dipyridamole is an antiplatelet agent chemically described as 2,2',2'',2'''-[(4,8-Dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]-tetraethanol. It has the following structural formula:
C24H40N8O4 Mol. Wt. 504.63
Dipyridamole is an odorless yellow crystalline substance, having a bitter taste. It is soluble in dilute acids, methanol and chloroform, and is practically insoluble in water.
Aspirin
The antiplatelet agent aspirin (acetylsalicylic acid) is chemically known as benzoic acid, 2‑ (acetyloxy)-, and has the following structural formula:
C9H8O4 Mol. Wt. 180.16
Aspirin is an odorless white needle-like crystalline or powdery substance. When exposed to moisture, aspirin hydrolyzes into salicylic and acetic acids, and gives off a vinegary odor. It is highly lipid soluble and slightly soluble in water.
Sources
Aspirin And Dipyridamole Manufacturers
- Teva Pharmaceuticals Usa Inc
![Aspirin And Dipyridamole Capsule [Teva Pharmaceuticals Usa Inc]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Aspirin And Dipyridamole | Teva Pharmaceuticals Usa Inc
Aspirin and extended-release dipyridamole capsules are not interchangeable with the individual components of aspirin and dipyridamole tablets.
The recommended dose of aspirin and extended-release dipyridamole capsules is one capsule given orally twice daily, one in the morning and one in the evening. Swallow capsules whole without chewing. Aspirin and extended-release dipyridamole capsules can be administered with or without food.
2.1 Alternative Regimen in Case of Intolerable HeadachesIn the event of intolerable headaches during initial treatment, switch to one capsule at bedtime and low-dose aspirin in the morning. Because there are no outcome data with this regimen and headaches become less of a problem as treatment continues, patients should return to the usual regimen as soon as possible, usually within one week.
- Roxane Laboratories, Inc.
Aspirin And Dipyridamole | Roxane Laboratories, Inc.
Aspirin and extended release dipyridamole capsules are not interchangeable with the individual components of aspirin and dipyridamole tablets.
The recommended dose of aspirin and extended release dipyridamole is one capsule given orally twice daily, one in the morning and one in the evening. Swallow capsules whole without chewing. Aspirin and extended release dipyridamole capsules can be administered with or without food.
2.1 Alternative Regimen in Case of Intolerable HeadachesIn the event of intolerable headaches during initial treatment, switch to one capsule at bedtime and low-dose aspirin in the morning. Because there are no outcome data with this regimen and headaches become less of a problem as treatment continues, patients should return to the usual regimen as soon as possible, usually within one week.
![Aspirin And Dipyridamole Capsule [Roxane Laboratories, Inc.]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=1f059a7a-8fd4-48a9-a36d-daa6dcc93c81&name=carton000160.jpg)
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