ATOPICA (cyclosporine) is a potent systemic immunosuppressant that may increase the susceptibility to infection and the development of neoplasia.
Not for human use. Keep this and all drugs out of reach of children. For use only in dogs.
Human Warnings:
Not for human use. Keep this and all drugs out of reach of children. For use only in dogs.
There is currently no manufacturer warning information available for this drug.
ATOPICA is indicated for the control of atopic dermatitis in dogs weighing at least 4 lbs body weight.
ATOPICA (cyclosporine capsules, USP) MODIFIED is an oral form of cyclosporine that immediately forms a microemulsion in an aqueous environment. Cyclosporine, the active ingredient in ATOPICA, is a cyclic polypeptide, immune modulating agent consisting of 11 amino acids. It is produced as a metabolite by the fungal species Beauveria nivea.
Chemically, cyclosporine A is designated [R-[R*,R*-(E)]]-cyclic-(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N, 4-dimethyl-L-2-amino-6-octenoyl-L- α -amino-butyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl). The structural formula is:
ATOPICA capsules contain cyclosporine formulated together with inactive ingredients.
ATOPICA is available in 10, 25, 50, and 100 mg capsule strengths in color-coded packaging for oral administration to dogs.