Benztropine Mesylate

Benztropine Mesylate

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Questions & Answers

Side Effects & Adverse Reactions

Safe use in pregnancy has not been established.

Benztropine mesylate may impair mental and/or physical abilities required for performance of hazardous tasks, such as operating machinery or driving a motor vehicle.

When benztropine mesylate is given concomitantly with phenothiazines, haloperidol, or other drugs with anticholinergic or antidopaminergic activity, patients should be advised to report gastrointestinal complaints, fever or heat intolerance promptly. Paralytic ileus, hyperthermia and heat stroke, all of which have sometimes been fatal, have occurred in patients taking anticholinergic-type antiparkinsonism drugs, including benztropine mesylate, in combination with phenothiazines and/or tricyclic antidepressants.

Since benztropine mesylate contains structural features of atropine, it may produce anhidrosis. For this reason, it should be administered with caution during hot weather, especially when given concomitantly with other atropine-like drugs to the chronically ill, the alcoholic, those who have central nervous system disease, and those who do manual labor in a hot environment. Anhidrosis may occur more readily when some disturbance of sweating already exists. If there is evidence of anhidrosis, the possibility of hyperthermia should be considered. Dosage should be decreased at the discretion of the physician so that the ability to maintain body heat equilibrium by perspiration is not impaired. Severe anhidrosis and fatal hyperthermia have occurred.

Legal Issues

There is currently no legal information available for this drug.

FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.

Uses

For use as an adjunct in the therapy of all forms of parkinsonism.

Useful also in the control of extrapyramidal disorders (except tardive dyskinesia - see PRECAUTIONS ) due to neuroleptic drugs (e.g., phenothiazines).

History

There is currently no drug history available for this drug.

Other Information

Benztropine mesylate is a synthetic compound containing structural features found in atropine and diphenhydramine.

It is designated chemically as 3a -(Diphenylmethoxy)-1aH, 5aH-tropane methanesulfonate. Its molecular formula is

C 21 H 25 NO•CH 4 O 3 S, and its structural formula is:

c1789516-figure-01

Benztropine mesylate is a crystalline white powder, very soluble in water, and has a molecular weight of 403.54.

Each benztropine mesylate tablet for oral administration contains benztropine mesylate 0.5 mg, 1 mg or 2 mg.

Inactive ingredients: colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, pregelatinized starch.

Benztropine Mesylate Manufacturers


  • Sunrise Pharmaceutical, Inc
    Benztropine Mesylate Tablet [Sunrise Pharmaceutical, Inc]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Avpak
    Benztropine Mesylate (Benztropine Mesylate) Tablet [Avpak]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Direct Rx
    Benztropine Mesylate Tablet [Direct Rx]
  • State Of Florida Doh Central Pharmacy
    Benztropine Mesylate Tablet [State Of Florida Doh Central Pharmacy]
  • Tya Pharmaceuticals
    Benztropine Mesylate Injection [Tya Pharmaceuticals]
  • Nexus Pharmaceuticals Inc
    Benztropine Mesylate Injection, Usp (Benztropine Mesylate) Injection [Nexus Pharmaceuticals Inc]
  • Rising Pharmaceuticals Inc
    Benztropine Mesylate Tablet [Rising Pharmaceuticals Inc]
  • State Of Florida Doh Central Pharmacy
    Benztropine Mesylate Tablet [State Of Florida Doh Central Pharmacy]
  • State Of Florida Doh Central Pharmacy
    Benztropine Mesylate Tablet [State Of Florida Doh Central Pharmacy]
  • Contract Pharmacy Services-pa
    Benztropine Mesylate Tablet [Contract Pharmacy Services-pa]
  • State Of Florida Doh Central Pharmacy
    Benztropine Mesylate Tablet [State Of Florida Doh Central Pharmacy]
  • Rebel Distributors Corp
    Benztropine Mesylate Tablet [Rebel Distributors Corp]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • American Regent, Inc.
    Benztropine Mesylate Injection, Solution [American Regent, Inc.]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Qualitest Pharmaceuticals
    Benztropine Mesylate Tablet [Qualitest Pharmaceuticals]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate (Benztropine Mesylate) Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate (Benztropine Mesylate) Tablet [Remedyrepack Inc. ]
  • Corepharma Llc.
    Benztropine Mesylate Tablet [Corepharma Llc.]
  • Pd-rx Pharmaceuticals, Inc.
    Benztropine Mesylate Tablet [Pd-rx Pharmaceuticals, Inc.]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Dispensing Solutions, Inc.
    Benztropine Mesylate Tablet [Dispensing Solutions, Inc.]
  • Cardinal Health
    Benztropine Mesylate Tablet [Cardinal Health]
  • Upsher-smith Laboratories, Inc.
    Benztropine Mesylate Tablet [Upsher-smith Laboratories, Inc.]
  • Mckesson Contract Packaging
    Benztropine Mesylate Tablet [Mckesson Contract Packaging]
  • Major Pharmaceuticals
    Benztropine Mesylate Tablet [Major Pharmaceuticals]
  • Ncs Healthcare Of Ky, Inc Dba Vangard Labs
    Benztropine Mesylate Tablet Benztropine Mesylate Tablet [Ncs Healthcare Of Ky, Inc Dba Vangard Labs]
  • Bryant Ranch Prepack
    Benztropine Mesylate Tablet [Bryant Ranch Prepack]
  • Bryant Ranch Prepack
    Benztropine Mesylate Tablet [Bryant Ranch Prepack]
  • Excellium Pharmaceutical, Inc,
    Benztropine Mesylate Tablet [Excellium Pharmaceutical, Inc,]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Ncs Healthcare Of Ky, Inc Dba Vangard Labs
    Benztropine Mesylate Tablet [Ncs Healthcare Of Ky, Inc Dba Vangard Labs]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Mckesson Contract Packaging
    Benztropine Mesylate Tablet [Mckesson Contract Packaging]
  • Cardinal Health
    Benztropine Mesylate Tablet [Cardinal Health]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Fresenius Kabi Usa, Llc
    Benztropine Mesylate Injection, Solution [Fresenius Kabi Usa, Llc]
  • Camber Pharmaceutical, Inc.
    Benztropine Mesylate Tablet [Camber Pharmaceutical, Inc.]
  • Pliva Inc.
    Benztropine Mesylate Tablet [Pliva Inc.]
  • Akorn, Inc.
    Benztropine Mesylate Injection [Akorn, Inc. ]
  • American Health Packaging
    Benztropine Mesylate Tablet [American Health Packaging]
  • Bayshore Pharmaceuticals, Llc
    Benztropine Mesylate Tablet [Bayshore Pharmaceuticals, Llc]
  • West-ward Pharmaceutical Corp
    Benztropine Mesylate Injection [West-ward Pharmaceutical Corp]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • State Of Florida Doh Central Pharmacy
    Benztropine Mesylate Tablet [State Of Florida Doh Central Pharmacy]
  • State Of Florida Doh Central Pharmacy
    Benztropine Mesylate Tablet [State Of Florida Doh Central Pharmacy]
  • Aphena Pharma Solutions – Tennessee, Llc
    Benztropine Mesylate Tablet [Aphena Pharma Solutions – Tennessee, Llc]
  • Clinical Solutions Wholesale
    Benztropine Mesylate Tablet [Clinical Solutions Wholesale]
  • Cardinal Health
    Benztropine Mesylate Tablet [Cardinal Health]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Tya Pharmaceuticals
    Benztropine Mesylate Tablet [Tya Pharmaceuticals]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Benztropine Mesylate Tablet [Remedyrepack Inc. ]

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