Dosage should be adjusted according to the severity of the pain and the response of the patient. However, it should be kept in mind that tolerance to hydrocodone can develop with continued use and that the incidence of untoward effects is dose related.
The usual adult dosage for Hydrocodone Bitartrate and Acetaminophen Tablets USP is:
Product Strength
Usual Adult Dosage as needed for pain
The total 24-hour dosage should not exceed
5 mg/325 mg
One to two tablets every four to six hours
12 tablets
5 mg/500 mg
One to two tablets every four to six hours
8 tablets
7.5 mg/325 mg
One tablet every four to six hours
8 tablets
7.5 mg/500 mg
One tablet every four to six hours
6 tablets
7.5 mg/650 mg
One tablet every four to six hours
6 tablets
7.5 mg/750 mg
One tablet every four to six hours
5 tablets
10 mg/325 mg
One tablet every four to six hours
6 tablets
10 mg/500 mg
One tablet every four to six hours
6 tablets
10 mg/650 mg
One tablet every four to six hours
6 tablets
10 mg/660 mg
One tablet every four to six hours
6 tablets
10 mg/750 mg
One tablet every four to six hours
5 tablets
