Clobetasol Propionate Lotion
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Manufacturer Warnings
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Uses
History
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Other Information
Clobetasol propionate lotion, 0.05% contains clobetasol propionate, a synthetic fluorinated corticosteroid, for topical use. The corticosteroids constitute a class of primarily synthetic steroids used topically as antiinflammatory and antipruritic agents. Clobetasol propionate is 21-chloro- 9-fluoro-11β, 17-dihydroxy-16β -methylpregna-1,4-diene-3,20-dione 17-propionate, with the empirical formula C25H32ClFO5, and a molecular weight of 466.98 (CAS Registry Number 25122-46-7).
The following is the chemical structure:
Clobetasol propionate is a white to almost white crystalline powder that is insoluble in water. Each gram of clobetasol propionate lotion, 0.05% contains 0.5 mg of clobetasol propionate, in a white lotion composed of carbomer 934P, dimethicone, isopropyl myristate, mineral oil, PEG-20 methyl glucose sesquistearate, propylene glycol, purified water, sodium hydroxide and white wax.
Sources
Clobetasol Propionate Lotion Manufacturers
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Taro Pharmaceuticals U.s.a., Inc.
![Clobetasol Propionate Lotion [Taro Pharmaceuticals U.s.a., Inc.]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Clobetasol Propionate Lotion | Taro Pharmaceuticals U.s.a., Inc.
Clobetasol propionate lotion, 0.05% is for topical use only, and not for ophthalmic, oral or intravaginal use.
Clobetasol propionate lotion, 0.05% should be applied to the affected skin areas twice daily and rubbed in gently and completely.
The total dosage should not exceed 50 g (50 mL or 1.75 fl. oz.) per week because of the potential for the drug to suppress the hypothalamicpituitary-adrenal (HPA) axis.
Clobetasol propionate lotion, 0.05% contains a topical corticosteroid; therefore treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that have not sufficiently improved after the initial 2 weeks of treatment with clobetasol propionate lotion, 0.05%.
Unless directed by physician, clobetasol propionate lotion, 0.05% should not be used with occlusive dressings.
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Actavis Mid Atlantic Llc
Clobetasol Propionate Lotion | Actavis Mid Atlantic Llc
Clobetasol Propionate Lotion, 0.05% is for topical use only, and not for ophthalmic, oral or intravaginal use.
Clobetasol Propionate Lotion, 0.05% should be applied to the affected skin areas twice daily and rubbed in gently and completely.
The total dosage should not exceed 50 g (50 mL or 1.75 fl. oz.) per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis.
Clobetasol Propionate Lotion, 0.05% contains a topical corticosteroid; therefore treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that have not sufficiently improved after the initial 2 weeks of treatment with Clobetasol Propionate Lotion, 0.05%.
Unless directed by physician, Clobetasol Propionate Lotion, 0.05% should not be used with occlusive dressings.
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Paddock Laboratories, Llc
Clobetasol Propionate Lotion | Paddock Laboratories, Llc
Clobetasol Propionate Lotion, 0.05% is for topical use only, and not for ophthalmic, oral or intravaginal use.
Clobetasol Propionate Lotion, 0.05%, should be applied to the affected skin areas twice daily and rubbed in gently and completely.
The total dosage should not exceed 50 g (50 mL or 1.75 fl. oz.) per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis.
Clobetasol Propionate Lotion, 0.05% contains a topical corticosteroid; therefore treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that have not sufficiently improved after the initial 2 weeks of treatment with Clobetasol Propionate Lotion, 0.05%.
Unless directed by physician, Clobetasol Propionate Lotion, 0.05% should not be used with occlusive dressings.
![Clobetasol Propionate Lotion [Actavis Mid Atlantic Llc]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=afd20e23-b7a6-46ca-bd8d-b7af9ff84201&name=35cd2027-figure-01.jpg)
![Clobetasol Propionate Lotion [Paddock Laboratories, Llc]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=4abecc19-e956-4d05-a51e-73dba23dc131&name=6cb5d2c9-29be-4ddd-ab67-e8e8a25a0a8d-03.jpg)
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