Diphenhydramine Hydrochloride

Diphenhydramine Hydrochloride

Diphenhydramine Hydrochloride Recall

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Questions & Answers

Side Effects & Adverse Reactions

Antihistamines should be used with considerable caution in patients with narrow-angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, symptomatic prostatic hypertrophy or bladder-neck obstruction.

Local necrosis has been associated with the use of subcutaneous or intradermal use of intravenous diphenhydramine.

 

In pediatric patients, especially, antihistamines in overdosage may cause hallucinations, convulsions or death.

As in adults, antihistamines may diminish mental alertness in pediatric patients. In the young pediatric patient, particularly, they may produce excitation.

 

Antihistamines are more likely to cause dizziness, sedation and hypotension in elderly patients.

 

Legal Issues

There is currently no legal information available for this drug.

FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.

Uses

Diphenhydramine Hydrochloride Injection is effective in adults and pediatric patients, other than premature infants and neonates, for the following conditions when the oral form is impractical:

 

For amelioration of allergic reactions to blood or plasma, in anaphylaxis as an adjunct to epinephrine and other standard measures after the acute symptoms have been controlled and for other uncomplicated allergic conditions of the immediate type when oral therapy is impossible or contraindicated.

 

For active treatment of motion sickness.

 

For use in parkinsonism, when oral therapy is impossible or contraindicated, as follows: parkinsonism in the elderly who are unable to tolerate more potent agents, mild cases of parkinsonism in other age groups and in other cases of parkinsonism in combination with centrally acting anticholinergic agents.

 

History

There is currently no drug history available for this drug.

Other Information

Diphenhydramine Hydrochloride Injection is a sterile, nonpyrogenic solution for intravenous or deep intramuscular use as an antihistaminic agent. Each mL contains diphenhydramine hydrochloride 50 mg and benzethonium chloride 100 mcg in Water for Injection. pH 4.0-6.5; sodium hydroxide and/or hydrochloric acid added, if needed, for pH adjustment.

The chemical name of diphenhydramine hydrochloride is 2-(Diphenylmethoxy)-N,N-dimethylethylamine hydrochloride. The structural formula is as follows:

MM1

C17H21NO • HCl MW 291.82

Diphenhydramine hydrochloride occurs as a white crystalline powder and is freely soluble in water and alcohol.

 

Diphenhydramine Hydrochloride Manufacturers


  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Injection [Remedyrepack Inc. ]
  • Proficient Rx Lp
    Diphenhydramine Hydrochloride Capsule [Proficient Rx Lp]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Capsule [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Capsule [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Capsule [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Capsule [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Capsule [Remedyrepack Inc. ]
  • A-s Medication Solutions Llc
    Diphenhydramine Hydrochloride Capsule [A-s Medication Solutions Llc]
  • A-s Medication Solutions Llc
    Diphenhydramine Hydrochloride Capsule [A-s Medication Solutions Llc]
  • A-s Medication Solutions Llc
    Diphenhydramine Hydrochloride Capsule [A-s Medication Solutions Llc]
  • A-s Medication Solutions Llc
    Diphenhydramine Hydrochloride Capsule [A-s Medication Solutions Llc]
  • Proficient Rx Lp
    Diphenhydramine Hydrochloride Capsule [Proficient Rx Lp]
  • State Of Florida Doh Central Pharmacy
    Diphenhydramine Hydrochloride Capsule [State Of Florida Doh Central Pharmacy]
  • Contract Pharmacy Services-pa
    Diphenhydramine Hydrochloride Capsule [Contract Pharmacy Services-pa]
  • Spirit Pharmaceuticals,llc
    Diphenhydramine Hydrochloride Capsule, Liquid Filled [Spirit Pharmaceuticals,llc]
  • Avema Pharma Solutions
    Diphenhydramine Hydrochloride Tablet, Coated [Avema Pharma Solutions]
  • Himprit Pharmachem Pvt Ltd
    Diphenhydramine Hydrochloride Tablet, Film Coated [Himprit Pharmachem Pvt Ltd]
  • Time-cap Labs, Inc
    Diphenhydramine Hydrochloride Tablet, Coated [Time-cap Labs, Inc]
  • West-ward Pharmaceutical Corp.
    Diphenhydramine Hydrochloride Injection [West-ward Pharmaceutical Corp.]
  • Eon Labs, Inc.
    Diphenhydramine Hydrochloride Capsule [Eon Labs, Inc.]
  • Dispensing Solutions, Inc.
    Diphenhydramine Hydrochloride Injection [Dispensing Solutions, Inc.]
  • Lake Erie Medical & Surgical Supply Dba Quality Care Products Llc
    Diphenhydramine Hydrochloride Capsule [Lake Erie Medical & Surgical Supply Dba Quality Care Products Llc]
  • Cardinal Health
    Diphenhydramine Hydrochloride Capsule [Cardinal Health]
  • Cardinal Health
    Diphenhydramine Hydrochloride Injection [Cardinal Health]
  • Rebel Distributors Corp
    Diphenhydramine Hydrochloride Injection [Rebel Distributors Corp]
  • Hospira, Inc.
    Diphenhydramine Hydrochloride Injection, Solution [Hospira, Inc.]
  • Physicians Total Care, Inc.
    Diphenhydramine Hydrochloride Capsule [Physicians Total Care, Inc.]
  • Physicians Total Care, Inc.
    Diphenhydramine Hydrochloride Liquid [Physicians Total Care, Inc.]
  • Physicians Total Care, Inc.
    Diphenhydramine Hydrochloride Liquid [Physicians Total Care, Inc.]
  • Major Pharmaceuticals
    Diphenhydramine Hydrochloride Capsule [Major Pharmaceuticals]
  • Simpex Pharma Pvt. Ltd
    Diphenhydramine Hydrochloride Tablet [Simpex Pharma Pvt. Ltd]
  • Qualitest Pharmaceuticals
    Diphenhydramine Hydrochloride Capsule [Qualitest Pharmaceuticals]
  • Qualitest Pharmaceuticals
    Diphenhydramine Hydrochloride Capsule [Qualitest Pharmaceuticals]
  • Aaa Pharmaceutical, Inc.
    Diphenhydramine Hydrochloride Tablet [Aaa Pharmaceutical, Inc.]
  • Aaa Pharmaceutical, Inc.
    Diphenhydramine Hydrochloride Tablet [Aaa Pharmaceutical, Inc.]
  • General Injectables And Vaccines
    Diphenhydramine Hydrochloride (Diphenhydramine Hydrochloride) Injection, Solution [General Injectables And Vaccines]
  • Aaa Pharmaceutical, Inc.
    Diphenhydramine Hydrochloride Tablet, Coated [Aaa Pharmaceutical, Inc.]
  • Bryant Ranch Prepack
    Diphenhydramine Hydrochloride Capsule [Bryant Ranch Prepack]
  • Advance Pharmaceutical Inc.
    Diphenhydramine Hydrochloride Capsule [Advance Pharmaceutical Inc.]
  • Advance Pharmaceutical Inc.
    Diphenhydramine Hydrochloride Capsule [Advance Pharmaceutical Inc.]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Capsule [Remedyrepack Inc. ]
  • Bd Rx Inc.
    Diphenhydramine Hydrochloride Injection, Solution [Bd Rx Inc.]
  • Humanwell Puracap Pharmaceutical (Wuhan), Ltd.
    Diphenhydramine Hydrochloride Capsule, Liquid Filled [Humanwell Puracap Pharmaceutical (Wuhan), Ltd.]
  • Mylan Institutional Llc
    Diphenhydramine Hydrochloride Injection, Solution [Mylan Institutional Llc]
  • Lake Erie Medical Dba Quality Care Products Llc
    Diphenhydramine Hydrochloride Capsule [Lake Erie Medical Dba Quality Care Products Llc]
  • Richmond Pharmaceuticals Inc.
    Diphenhydramine Hydrochloride Capsule [Richmond Pharmaceuticals Inc.]
  • Bonita Pharmaceuticals Llc
    Diphenhydramine Hydrochloride Tablet, Coated [Bonita Pharmaceuticals Llc]
  • Unit Dose Services
    Diphenhydramine Hydrochloride Capsule [Unit Dose Services]
  • A-s Medication Solutions Llc
    Diphenhydramine Hydrochloride Capsule [A-s Medication Solutions Llc]
  • A-s Medication Solutions Llc
    Diphenhydramine Hydrochloride Capsule [A-s Medication Solutions Llc]
  • General Injectables & Vaccines, Inc
    Diphenhydramine Hydrochloride Injection, Solution [General Injectables & Vaccines, Inc]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Injection [Remedyrepack Inc. ]
  • A-s Medication Solutions Llc
    Diphenhydramine Hydrochloride Capsule [A-s Medication Solutions Llc]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Injection [Remedyrepack Inc. ]
  • Advance Pharmaceutical Inc.
    Diphenhydramine Hydrochloride Tablet [Advance Pharmaceutical Inc.]
  • Ncs Healthcare Of Ky, Inc Dba Vangard Labs
    Diphenhydramine Hydrochloride Capsule [Ncs Healthcare Of Ky, Inc Dba Vangard Labs]
  • Lake Erie Medical Dba Quality Care Products Llc
    Diphenhydramine Hydrochloride Capsule [Lake Erie Medical Dba Quality Care Products Llc]
  • Cardinal Health
    Diphenhydramine Hydrochloride Injection [Cardinal Health]
  • Humanwell Puracap Pharmaceutical (Wuhan), Ltd.
    Diphenhydramine Hydrochloride Capsule, Liquid Filled [Humanwell Puracap Pharmaceutical (Wuhan), Ltd.]
  • Preferred Pharmaceuticals, Inc.
    Diphenhydramine Hydrochloride Capsule [Preferred Pharmaceuticals, Inc.]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Injection [Remedyrepack Inc. ]
  • Humanwell Puracap Pharmaceutical (Wuhan), Ltd.
    Diphenhydramine Hydrochloride Capsule, Liquid Filled [Humanwell Puracap Pharmaceutical (Wuhan), Ltd.]
  • Hospira, Inc.
    Diphenhydramine Hydrochloride Injection, Solution [Hospira, Inc.]
  • Direct Rx
    Diphenhydramine Hydrochloride Capsule [Direct Rx]
  • Bryant Ranch Prepack
    Diphenhydramine Hydrochloride Capsule [Bryant Ranch Prepack]
  • Clinical Solutions Wholesale
    Diphenhydramine Hydrochloride Capsule [Clinical Solutions Wholesale]
  • Clinical Solutions Wholesale
    Diphenhydramine Hydrochloride Capsule [Clinical Solutions Wholesale]
  • Humanwell Puracap Pharmaceutical (Wuhan), Ltd.
    Diphenhydramine Hydrochloride Capsule, Liquid Filled [Humanwell Puracap Pharmaceutical (Wuhan), Ltd.]
  • Humanwell Puracap Pharmaceutical (Wuhan), Ltd.
    Diphenhydramine Hydrochloride Capsule, Liquid Filled [Humanwell Puracap Pharmaceutical (Wuhan), Ltd.]
  • Tya Pharmaceuticals
    Diphenhydramine Hydrochloride Capsule [Tya Pharmaceuticals]
  • Cardinal Health
    Diphenhydramine Hydrochloride Injection, Solution [Cardinal Health]
  • Humanwell Puracap Pharmaceutical (Wuhan), Ltd.
    Diphenhydramine Hydrochloride Capsule, Liquid Filled [Humanwell Puracap Pharmaceutical (Wuhan), Ltd.]
  • Lake Erie Medical Dba Quality Care Products Llc
    Diphenhydramine Hydrochloride Capsule [Lake Erie Medical Dba Quality Care Products Llc]
  • Remedyrepack Inc.
    Diphenhydramine Hydrochloride Capsule [Remedyrepack Inc. ]

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