Dmsa
Loading...Dmsa Recall
Get an alert when a recall is issued.
Questions & Answers
Side Effects & Adverse Reactions
None.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
DMSA is to be used as an aid in the scintigraphic evaluation of renal parenchymal disorders.
History
There is currently no drug history available for this drug.
Other Information
Each vial contains a sterile, pyrogen-free freeze-dried mixture of 1.0 mg dimercaptosuccinic acid, 0.42 mg stannous chloride dihydrate [0.38 mg (minimum) stannous chloride dihydrate (SnCl2•2H2O) and 0.46 mg (maximum) total tin expressed as stannous chloride dihydrate (SnCl2•2H2O)], 0.70 mg ascorbic acid, and 50.0 mg inositol. After freeze-drying, vials are sealed under a nitrogen atmosphere with a rubber closure. Sodium hydroxide and hydrochloric acid have been used for pH adjustment. When sterile, oxidant-free, pyrogen-free sodium pertechnetate Tc99m injection in isotonic saline is combined with the vial contents, following the instructions provided with the kit, a complex is formed. After 10 minutes incubation the reconstituted solution is ready for intravenous injection.
Chemical Name: meso-2,3-dimercaptosuccinic acid
The succimer component of DMSA consists of more than 90% meso isomer and less than 10% d,l isomer.
Sources
Dmsa Manufacturers
-
Ge Healthcare
![Dmsa (Dimercaptosuccinic Acid) Injection, Powder, Lyophilized, For Solution [Ge Healthcare]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Dmsa | Ge Healthcare
The suggested dose range for slow I.V. administration to be employed in the average patient (70 kg) for renal parenchymal imaging is 74-222 MBq, 2-6 mCi technetium Tc99m succimer injection.
The product must be used between 10 minutes to 4 hours following preparation (see "Preparation" section). Acceptable renal images may be obtained beginning 1 to 2 hours post injection. Any unused portion should be discarded after that time.
The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration.
Do not use after the expiration date stated on the label. The components of the kit are supplied sterile and pyrogen-free. Aseptic procedures normally employed in making additions and withdrawals from sterile, pyrogen-free containers should be used during addition of sodium pertechnetate Tc99m injection solutions and during the withdrawal of doses for patient administration.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration.
Login To Your Free Account