FDA records indicate that there are no current recalls for this drug.
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Donepezil Hydrochloride 5 Mg Recall
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Questions & Answers
Side Effects & Adverse Reactions
For external use only.
Avoid contact with eyes and mucous membranes.
Keep out of reach of children.
Consult your veterinarian before use.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
EquiShield® CK HC Shampoo is an antiseptic and anti-inflammatory shampoo designed for horses, dogs and cats.
History
There is currently no drug history available for this drug.
Other Information
There are no additional details available for this product.
Sources
Donepezil Hydrochloride 5 Mg Manufacturers
- Cardinal Health
Donepezil Hydrochloride 5 Mg | Kinetic Technologies
Shake well before use. Wet the hair coat with warm water and apply a sufficient amount of shampoo to create a rich lather. Massage medicated shampoo into wet hair coat. Rinse and repeat. Allow to remain on hair coat for 5 to 10 minutes, then rinse thoroughly with clean water. May be used initially 2-3 times weekly for 4 weeks. Then reduce to 1 time weekly or as directed by your veterinarian.
- Northstar Rxllc
Donepezil Hydrochloride 5 Mg | Northstar Rxllc
Donepezil hydrochloride tablets should be taken in the evening, just prior to retiring.
Donepezil hydrochloride tablets can be taken with or without food.The dosages of donepezil hydrochloride shown to be effective in controlled clinical trials are 5 mg and 10 mg administered once per day.
The higher dose of 10 mg did not provide a statistically significantly greater clinical benefit than 5 mg. There is a suggestion, however, based upon order of group mean scores and dose trend analyses of data from these clinical trials, that a daily dose of 10 mg of donepezil hydrochloride might provide additional benefit for some patients. Accordingly, whether or not to employ a dose of 10 mg is a matter of prescriber and patient preference.
2.2. Moderate to Severe Alzheimer's Disease
Donepezil hydrochloridehas been shown to be effective in controlled clinical trials at a dose of 10 mg administered once daily.The recommended starting dose of donepezil hydrochloride is 5 mg once daily. Evidence from the controlled trials in mild to moderate Alzheimer’s disease indicates that the 10 mg dose, with a one week titration, is likely to be associated with a higher incidence of cholinergic adverse events compared to the 5 mg dose. In open-label trials using a 6 week titration, the type and frequency of these same adverse events were similar between the 5 mg and 10 mg dose groups. Therefore, because donepezil hydrochloride steady state is achieved about 15 days after it is started and because the incidence of untoward effects may be influenced by the rate of dose escalation, a dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks.
- Alembic Pharmaceuticals Limited
Donepezil Hydrochloride 5 Mg | Alembic Pharmaceuticals Limited
Donepezil hydrochloride tablets should be taken in the evening, just prior to retiring.
Donepezil hydrochloride tablets can be taken with or without food.
2.1. Mild to Moderate Alzheimer's DiseaseThe dosages of donepezil hydrochloride shown to be effective in controlled clinical trials are 5 mg and 10 mg administered once per day.
The higher dose of 10 mg did not provide a statistically significantly greater clinical benefit than 5 mg. There is a suggestion, however, based upon order of group mean scores and dose trend analyses of data from these clinical trials, that a daily dose of 10 mg of donepezil hydrochloride might provide additional benefit for some patients. Accordingly, whether or not to employ a dose of 10 mg is a matter of prescriber and patient preference.
2.2. Moderate to Severe Alzheimer's DiseaseDonepezil hydrochloridehas been shown to be effective in controlled clinical trials at a dose of 10 mg administered once daily.
2.3. TitrationThe recommended starting dose of donepezil hydrochloride is 5 mg once daily. Evidence from the controlled trials in mild to moderate Alzheimer’s disease indicates that the 10 mg dose, with a one week titration, is likely to be associated with a higher incidence of cholinergic adverse events compared to the 5 mg dose. In open-label trials using a 6 week titration, the type and frequency of these same adverse events were similar between the 5 mg and 10 mg dose groups. Therefore, because donepezil hydrochloride steady state is achieved about 15 days after it is started and because the incidence of untoward effects may be influenced by the rate of dose escalation, a dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks.
- Major Pharmaceuticals
Donepezil Hydrochloride 5 Mg | Major Pharmaceuticals
Donepezil hydrochloride tablets should be taken in the evening, just prior to retiring.
Donepezil hydrochloride tablets can be taken with or without food.The dosages of donepezil hydrochloride shown to be effective in controlled clinical trials are 5 mg and 10 mg administered once per day.
The higher dose of 10 mg did not provide a statistically significantly greater clinical benefit than 5 mg. There is a suggestion, however, based upon order of group mean scores and dose trend analyses of data from these clinical trials, that a daily dose of 10 mg of donepezil hydrochloride might provide additional benefit for some patients. Accordingly, whether or not to employ a dose of 10 mg is a matter of prescriber and patient preference.
2.2. Moderate to Severe Alzheimer's Disease
Donepezil hydrochloridehas been shown to be effective in controlled clinical trials at a dose of 10 mg administered once daily.The recommended starting dose of donepezil hydrochloride is 5 mg once daily. Evidence from the controlled trials in mild to moderate Alzheimer’s disease indicates that the 10 mg dose, with a one week titration, is likely to be associated with a higher incidence of cholinergic adverse events compared to the 5 mg dose. In open-label trials using a 6 week titration, the type and frequency of these same adverse events were similar between the 5 mg and 10 mg dose groups. Therefore, because donepezil hydrochloride steady state is achieved about 15 days after it is started and because the incidence of untoward effects may be influenced by the rate of dose escalation, a dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks.
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