Econochlor
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Questions & Answers
Side Effects & Adverse Reactions
SEE BOX WARNING.
Ophthalmic ointment may retard corneal wound healing.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Chloramphenicol should be used only in those serious infections for which less potentially dangerous drugs are ineffective or contraindicated. Bacteriological studies should be performed to determine the causative organisms and their sensitivity to chloramphenicol (See Box Warning). For treatment of ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms.
Chloramphenicol has a wide spectrum of antimicrobial activity and is effective against many gram negative and gram positive bacteria, including the following common eye pathogens:
Staphylococcus aureus
Streptococci, including Streptococcus pneumoniae
Escherichia coli
Haemophilus influenzae
Klebsiella/Enterobacter species
Neisseria species
Moraxella lacunata (Morax-Axenfeld bacillus)
The product does not provide adequate coverage against:
Pseudomonas aeruginosa
Serratia marcescens
History
There is currently no drug history available for this drug.
Other Information
ECONOCHLOR® (Chloramphenicol) is a sterile topical ophthalmic antibacterial prepared in solution and ointment forms. The active ingredient is represented by the chemical structure:
Established name:
Chloramphenicol
Chemical name:
Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2- (4-nitrophenyl) ethyl]-, [R-(R*,R)]-
Each ml of solution contains: Active: Chloramphenicol 0.5% (5mg/ml). Preservative: Thimerosal 0.01%. Vehicle: Hydroxypropyl Methylcellulose: Inactive: Boric Acid, Sodium Borate (to adjust pH), Purified Water.
DM-00
Each gram of ointment contains: Active: Chloramphenicol 1.0% (10 mg/g). Inactive: Mineral Oil, Anhydrous Liquid Lanolin, White Petrolatum.
DM-00
Sources
Econochlor Manufacturers
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Alcon Laboratories, Inc.
![Econochlor (Chloramphenicol) Solution Econochlor (Chloramphenicol) Ointment [Alcon Laboratories, Inc.]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Econochlor | Alcon Laboratories, Inc.
Solution: In severe disease, instill two drops on the eye(s) hourly until improvement, following which treatment should be diminished prior to discontinuation. In mild disease, drops may be used four times daily. Ointment: Apply a small amount to the lower conjunctival sac(s) at bedtime as a supplement to the drops.
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