Ephedrine Sulfate

Ephedrine Sulfate

Ephedrine Sulfate Recall

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Questions & Answers

Side Effects & Adverse Reactions

Ephedrine may cause hypertension resulting in intracranial hemorrhage. Ephedrine may induce anginal pain in patients with coronary insufficiency or ischemic heart disease. The drug also may induce potentially fatal arrhythmias in patients with organic heart disease or who are receiving drugs that sensitize the myocardium. See CONTRAINDICATIONS.

Initially, parenterally administered ephedrine may produce constriction of renal blood vessels and decreased urine formation.

Legal Issues

There is currently no legal information available for this drug.

FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.


Ephedrine Sulfate Injection, USP is indicated primarily to counteract the hypotensive effects of spinal or other types of nontopical conduction anesthesia. It is also useful as a pressor agent in hypotensive states following sympathectomy, or following overdosage with ganglionic-blocking agents, antiadrenergic agents, veratrum alkaloids or other drugs used for lowering blood pressure in the treatment of arterial hypertension. The drug is sometimes injected to relieve acute bronchospasm, but it is less effective than epinephrine for this purpose.


There is currently no drug history available for this drug.

Other Information

Ephedrine Sulfate Injection, USP is a sterile, nonpyrogenic solution containing ephedrine sulfate 50 mg/mL in water for injection. It is administered by subcutaneous, intramuscular or intravenous injection as an adrenergic agent. The solution contains no bacteriostat, antimicrobial agent or added buffer. The pH is 5.3 (4.5 to 7.0). The osmolar concentration of the 5% solution is 0.35 mOsmol/mL (calc.).

Ephedrine Sulfate, USP is a sympathomimetic amine chemically designated α-[1-(methylamino) ethyl] benzenemethanol sulfate (2:1)(salt). It has the following structural formula:

Chemical Structure

Ephedrine Sulfate Manufacturers

  • Andersen Pharma Llc
    Ephedrine Sulfate Injection, Solution [Andersen Pharma Llc]
  • West-ward Pharmaceutical Corp
    Ephedrine Sulfate Capsule [West-ward Pharmaceutical Corp]
  • Sandoz Inc
    Ephedrine Sulfate Injection, Solution [Sandoz Inc]
  • Akorn, Inc.
    Ephedrine Sulfate Injection [Akorn, Inc.]
  • Akorn, Inc.
    Ephedrine Sulfate Injection [Akorn, Inc.]
  • Cardinal Health
    Ephedrine Sulfate Injection [Cardinal Health]
  • Cardinal Health
    Ephedrine Sulfate Injection, Solution [Cardinal Health]

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