Eprinex Pour-on For Cattle

Eprinex Pour-on For Cattle

Eprinex Pour-on For Cattle Recall

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Questions & Answers

Side Effects & Adverse Reactions

Keep this and all drugs out of the reach of children.
NOT FOR USE IN HUMANS.

As with any topical medication intended for treatment of animals, skin contact should be avoided. If accidental skin contact occurs, wash immediately with soap and water. If accidental eye exposure occurs, flush eyes immediately with water. The material safety data sheet (MSDS) contains more detailed occupational safety information.

To report adverse effects, obtain an MSDS or for assistance, contact Merial at 1-888-637-4251.

Legal Issues

There is currently no legal information available for this drug.

FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.

Uses

There is currently no usage information available for this product. We apologize for any inconvenience.

History

There is currently no drug history available for this drug.

Other Information

EPRINEX Pour-On delivers effective internal and external parasite control in one application. Discovered and developed by scientists from Merck Research Laboratories, EPRINEX Pour-On contains eprinomectin, a unique avermectin. Its broad-spectrum efficacy in a weatherproof formulation, margin of safety, zero slaughter withdrawal and zero milk discard, make it a convenient product for parasite control in beef and dairy cattle, including lactating dairy cattle.

MODE OF ACTION

Eprinomectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells.

This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA).

The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated chloride channels, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier.

Eprinex Pour-on For Cattle Manufacturers


  • Merial Limited
    Eprinex Pour-on For Cattle (Eprinomectin) Solution [Merial Limited]

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