Excede For Swine Sterile
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Questions & Answers
Side Effects & Adverse Reactions
FOR USE IN ANIMALS ONLY. NOT FOR HUMAN USE. KEEP OUT OF REACH OF CHILDREN.
Penicillins and cephalosporins can cause allergic reactions in sensitized individuals. Topical exposures to such antimicrobials, including ceftiofur, may elicit mild to severe allergic reactions in some individuals. Repeated or prolonged exposure may lead to sensitization. Avoid direct contact of the product with the skin, eyes, mouth and clothing. Sensitization of the skin may be avoided by wearing protective gloves.
Persons with a known hypersensitivity to penicillin or cephalosporins should avoid exposure to this product.
In case of accidental eye exposure, flush with water for 15 minutes. In case of accidental skin exposure, wash with soap and water. Remove contaminated clothing. If allergic reaction occurs (e.g., skin rash, hives, difficult breathing), seek medical attention.
The material safety data sheet contains more detailed occupational safety information. To report adverse effects in users, to obtain more information or to obtain a material safety data sheet, call 1-888-963-8471.
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FDA Safety Alerts
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Manufacturer Warnings
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FDA Labeling Changes
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Uses
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History
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Other Information
EXCEDE FOR SWINE Sterile Suspension 100 mg/mL is a ready-to-use formulation that contains the crystalline free acid of ceftiofur, which is a broad spectrum cephalosporin antibiotic active against gram-positive and gram-negative bacteria including ß-lactamase-producing strains. Like other cephalosporins, ceftiofur is bactericidal in vitro, resulting from inhibition of cell wall synthesis.
Each mL of this ready-to-use sterile suspension contains ceftiofur crystalline free acid equivalent to 100 mg ceftiofur, in a Miglyol® and cottonseed oil based suspension.
Figure 1. Structure of ceftiofur crystalline free acid:
Chemical name of ceftiofur crystalline free acid:
7-[[2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene 2-carboxylic acid
Sources
Excede For Swine Sterile Manufacturers
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Zoetis Inc.
![Excede For Swine Sterile (Ceftiofur) Injection, Suspension [Zoetis Inc.]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Excede For Swine Sterile | Zoetis Inc.
DOSAGE
Administer by intramuscular (IM) injection in the post-auricular region of the neck as a single dosage of 2.27 mg ceftiofur equivalents (CE)/lb (5.0 mg CE/kg) body weight (BW). This is equivalent to 1 mL sterile suspension per 44 lb (20 kg) BW. No more than 2 mL should be injected in a single injection site. Injection volumes in excess of 2 mL per injection site may result in violative residues. Pigs heavier than 88 lb (40 kg) will require more than one injection.
Most animals will respond to treatment within three to five days. If no improvement is observed, the diagnosis should be re-evaluated.
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