Flublok
Loading...Flublok Recall
Get an alert when a recall is issued.
Questions & Answers
Side Effects & Adverse Reactions
There is currently no warning information available for this product. We apologize for any inconvenience.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Flublok is a vaccine indicated for active immunization against disease caused by influenza virus subtypes A and type B contained in the vaccine. Flublok is approved for use in persons 18 through 49 years of age.
History
There is currently no drug history available for this drug.
Other Information
Flublok [Influenza Vaccine] is a sterile, clear, colorless solution of recombinant hemagglutinin (HA) proteins from three influenza viruses for intramuscular injection. It contains purified HA proteins produced in a continuous insect cell line (expresSF+®) that is derived from Sf9 cells of the fall armyworm, Spodoptera frugiperda, and grown in serum-free medium composed of chemically-defined lipids, vitamins, amino acids, and mineral salts. Each of the three HAs is expressed in this cell line using a baculovirus vector (Autographa californica nuclear polyhedrosis virus), extracted from the cells with Triton X-100 and further purified by column chromatography. The purified HAs are then blended and filled into single-dose vials.
Flublok is standardized according to United States Public Health Service (USPHS) requirements. For the 2012 - 2013 influenza season it is formulated to contain 135 mcg HA per 0.5 mL dose, with 45 mcg HA of each of the following 3 influenza virus strains: A/California/7/2009 (H1N1), A/Victoria/361/2011 (H3N2), and B/Wisconsin/1/2010.
A single 0.5 mL dose of Flublok contains sodium chloride (4.4 mg), monobasic sodium phosphate (0.195 mcg), dibasic sodium phosphate (1.3 mg), and polysorbate 20 (Tween®20) (27.5 mcg). Each 0.5 mL dose of Flublok may also contain residual amounts of baculovirus and host cell proteins (≤ 28.5 mcg), baculovirus and cellular DNA (≤ 10 ng), and Triton X-100 (≤ 100 mcg).
Flublok contains no egg proteins, antibiotics, or preservatives. The stoppers used for the single-dose vials do not contain latex.
Sources
Flublok Manufacturers
-
Protein Sciences Corporation
![Flublok (Influenza Vaccine) Injection, Solution [Protein Sciences Corporation]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Flublok | Protein Sciences Corporation
For intramuscular injection only.
2.1 DosageAdminister Flublok as a single 0.5-mL dose.
2.2 AdministrationShake the single-dose vial gently before withdrawing the vaccine dose.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permits. If either of these conditions exists, the vaccine should not be administered.
The preferred site for injection is the deltoid muscle. Administration is by sterile needle and syringe.
Flublok should not be mixed with any other vaccine in the same syringe or vial.
-
Protein Sciences Corporation
Flublok | Protein Sciences Corporation
For intramuscular injection only.
2.1 DosageAdminister Flublok as a single 0.5-mL dose.
2.2 AdministrationShake the single-dose vial gently before withdrawing the vaccine dose.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permits. If either of these conditions exists, the vaccine should not be administered.
The preferred site for injection is the deltoid muscle. Administration is by sterile needle and syringe.
Flublok should not be mixed with any other vaccine in the same syringe or vial.
-
Protein Sciences Corporation
Flublok | Protein Sciences Corporation
For intramuscular injection only.
2.1 DosageAdminister Flublok as a single 0.5-mL dose.
2.2 AdministrationShake the single-dose vial gently before withdrawing the vaccine dose.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permits. If either of these conditions exists, the vaccine should not be administered.
The preferred site for injection is the deltoid muscle. Administration is by sterile needle and syringe.
Flublok should not be mixed with any other vaccine in the same syringe or vial.
![Flublok (Influenza Vaccine) Injection, Solution [Protein Sciences Corporation]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=fb2aad7e-82d2-47c0-9eb3-08ac62641a47&name=fb2aad7e-82d2-47c0-9eb3-08ac62641a47-01.jpg)
![Flublok (Influenza Vaccine) Injection, Solution [Protein Sciences Corporation]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=c94cbe57-4a3a-4a3e-8bb8-2f07e936848e&name=image-01.jpg)
Login To Your Free Account