Good Sense Pain Relief

Good Sense Pain Relief Manufacturers

• L Perrigo Company
  

  ×

  Good Sense Pain Relief | L Perrigo Company

  

  ---

  do not take more than directed (see Liver warning) adults and children 12 years and over take 2 tablets every 4 to 6 hours while symptoms last do not take more than 12 tablets in 24 hours

  children

  6-11 years take 1 tablet every 4 to 6 hours while symptoms last do not take more than 5 tablets in 24 hours

  children under

  6 years do not use this adult Regular Strength product in children under 6 years of age; this will provide more than the recommended dose (overdose) and may cause liver damage

  Close
  No Recall

  More Info
• L. Perrigo Company
  

  ×

  Good Sense Pain Relief | L. Perrigo Company

  

  ---

  • do not take more than directed (see Liver warning)

  adults and children

  12 years and over

  • take 2 caplets every 6 hours while symptoms last • do not take more than 6 caplets in 24 hours, unless directed by a doctor • do not use for more than 10 days unless directed by a doctor

  children under 12 years

  ask a doctor

  Close
  No Recall

  More Info
• L. Perrigo Company
  

  ×

  Good Sense Pain Relief | Mylan Pharmaceuticals Inc.

  

  ---

  2.1 Adults – Treatment of HIV-1 Infection Oral Dosing

  The recommended oral dose of zidovudine tablets is 300 mg twice daily in combination with other antiretroviral agents.

  2.2 Pediatric Patients (Aged 4 Weeks to Less Than 18 Years)

  Healthcare professionals should pay special attention to accurate calculation of the dose of zidovudine tablets, transcription of the medication order, dispensing information, and dosing instructions to minimize risk for medication dosing errors.

  Prescribers should calculate the appropriate dose of zidovudine tablets for each child based on body weight (kg) and should not exceed the recommended adult dose.

  Before prescribing zidovudine tablets, children should be assessed for the ability to swallow tablets. If a child is unable to reliably swallow a zidovudine tablet, the zidovudine syrup formulation should be prescribed.

  The recommended oral dosage in pediatric patients aged 4 weeks to less than 18 years and weighing greater than or equal to 4 kg is provided in Table 1. Zidovudine syrup should be used to provide accurate dosage when whole tablets are not appropriate.

  Table 1: Recommended Pediatric Oral Dosage of Zidovudine Tablets

  Body Weight (kg)

  Total Daily Dose

  Dosage Regimen and Dose

  Twice Daily

  Three Times Daily

  4 to < 9

  24 mg/kg/day

  12 mg/kg

  8 mg/kg

  ≥ 9 to < 30

  18 mg/kg/day

  9 mg/kg

  6 mg/kg

  ≥ 30

  600 mg/day

  300 mg

  200 mg

  Alternatively, dosing for zidovudine tablets can be based on body surface area (BSA) for each child. The recommended oral dose of zidovudine tablets is 480 mg per m2 per day in divided doses (240 mg per m2 twice daily or 160 mg per m2 three times daily). In some cases the dose calculated by mg per kg will not be the same as that calculated by BSA.

  2.3 Prevention of Maternal-Fetal HIV-1 Transmission

  The recommended dosage regimen for administration to pregnant women (greater than 14 weeks of pregnancy) and their neonates is:

  Maternal Dosing

  100 mg orally 5 times per day until the start of labor [see Clinical Studies (14.3)]. During labor and delivery, intravenous zidovudine should be administered at 2 mg per kg (total body weight) over 1 hour followed by a continuous intravenous infusion of 1 mg per kg per hour (total body weight) until clamping of the umbilical cord.

  Neonatal Dosing

  Start neonatal dosing within 12 hours after birth and continue through 6 weeks of age. Neonates unable to receive oral dosing may be administered zidovudine intravenously. See Table 2.

  Table 2. Recommended Neonatal Dosages of Zidovudine

  Route

  Total Daily Dose

  Dose and Dosage Regimen

  Oral

  8 mg/kg/day

  2 mg/kg every 6 hours

  Intravenous

  6 mg/kg/day

  1.5 mg/kg infused over 30 minutes, every 6 hours

  2.4 Patients with Severe Anemia and/or Neutropenia

  Significant anemia (hemoglobin less than 7.5 g per dL or reduction greater than 25% of baseline) and/or significant neutropenia (granulocyte count less than 750 cells per mm3 or reduction greater than 50% from baseline) may require a dose interruption until evidence of marrow recovery is observed [see Warnings and Precautions (5.1)]. In patients who develop significant anemia, dose interruption does not necessarily eliminate the need for transfusion. If marrow recovery occurs following dose interruption, resumption in dose may be appropriate using adjunctive measures such as epoetin alfa at recommended doses, depending on hematologic indices such as serum erythropoietin level and patient tolerance.

  2.5 Patients with Renal Impairment

  In patients maintained on hemodialysis or peritoneal dialysis or with creatinine clearance (CrCl) by Cockcroft-Gault less than 15 mL per min, the recommended oral dosage is 100 mg every 6 to 8 hours [see Use in Specific Populations (8.6), Clinical Pharmacology (12.3)].

  2.6 Patients with Hepatic Impairment

  There are insufficient data to recommend dose adjustment of zidovudine tablets in patients with impaired hepatic function or liver cirrhosis. Frequent monitoring of hematologic toxicities is advised [see Use in Specific Populations (8.7)].

  Close
  No Recall

  More Info
• L Perrigo Company
  

  ×

  Good Sense Pain Relief | L Perrigo Company

  

  ---

  • this product does not contain directions or complete warnings for adult use • do not give more than directed (see Liver warning) • shake well before using • find right dose on chart. If possible, use weight to dose; otherwise, use age. • use only enclosed dosing cup designed for use with this product. Do not use any other dosing device. • if needed, repeat dose every 4 hours while symptoms last • do not give more than 5 times in 24 hours • do not give for more than 5 days unless directed by a doctor

  Weight (lb)

  Age (yr)

  Dose (tsp or mL)

  under 24

  under 2 years

  ask a doctor

  24-35

  2-3 years

  1 tsp or 5 mL

  36-47

  4-5 years

  1 ½ tsp or 7.5 mL

  48-59

  6-8 years

  2 tsp or 10 mL

  60-71

  9-10 years

  2 ½ tsp or 12.5 mL

  72-95

  11 years

  3 tsp or 15 mL

  Attention: use only enclosed dosing cup specifically designed for use with this product. Do not use any other dosing device.

  Close
  No Recall

  More Info
• L. Perrigo Company
  

  ×

  Good Sense Pain Relief | L. Perrigo Company

  

  ---

  • do not take more than directed (see overdose warning)

  adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last • do not take more than 6 caplets in 24 hours, unless directed by a doctor • do not use for more than 10 days unless directed by a doctor

  children under

  12 years

  ask a doctor

  Close
  No Recall

  More Info