Heartworm Preventative & Intestinal Parasite Treatment (ivermectin/pyrantel pamoate/praziquantel) Chewable Tablets should be administerd orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb), 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) and 5 mg of praziquantel per kg (2.27 mg/lb) of body weight, as follows:
Dog Weight Lbs.
Chewable Tablet Per Month
Tablet Size
Ivermectin Content
Pyrantel Pamoate Content
Praziquantel Content
6.0 to 12
1
Toy
34 mcg
28.5 mg
28.5 mg
12.1 to 25
1
Small
68 mcg
57 mg
57 mg
25.1 to 50
1
Medium
136 mcg
114 mg
114 mg
50.1 to 100
1
Large
272 mcg
228 mg
228 mg
Heartworm Preventative & Intestinal Parasite Treatment Chewable Tablets are recommended for 8 weeks of age and older. For dogs over 100 lbs, use the appropriate of these Chewable Tablets.
Remove only one tablet at a time from the foil-backed blister card. Return the remaining tablets to their box to protect the product from light. Heartworm Preventative & Intestinal Parasite Treatment Chewable Tablets can be offered to the dog by hand or be added intact to a small amount of dog food. Care should be taken that the dog consumes the complete dose, and the dog should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.
Heartworm Preventative & Intestinal Parasite Treatment Chewable Tablets should be given at monthly intervals during the period of the year when mosquitoes (vectors), potentially carrying infective heartworm larvae, are active. The initial dose must be given within a month (30 days) after the dog's first exposure to mosquitoes. The final dose must be given within a month (30 days) after the dog's last exposure to mosquitoes.
When replacing another heartworm preventive product in a heartworm disease prevention program, the first dose of Heartworm Preventative & Intestinal Parasite Treatment Chewable Tablets must be given within a month (30 days) of the last dose of the former medication. A heartworm test should be performed prior to switching heartworm preventive products.
If the interval between doses exceeds a month (30 days), the efficacy of ivermectin can be reduced. Therefore, for optimal performance, the tablet must be given once a month on or about the same day of the month. If treatment is delayed, whether by a few days or many, immediate treatment with Heartworm Preventative & Intestinal Parasite Treatment Chewable Tablets and resumption of the recommended dosing regimen will minimize the opportunity for the development of adult heartworms.
