Hepatitis-sode Recall

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Provocholine®(methacholine chloride powder for inhalation) is indicated for the diagnosis of bronchial airway hyperreactivity in subjects who do not have clinically apparent asthma.


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Other Information

Provocholine® (methacholine chloride powder for inhalation) is a parasympathomimetic (cholinergic)) bronchoconstrictor agent to be administered in solution only, by inhalation, for diagnostic purposes. Each 20 mL vial contains 100 mg and each 50 mL vial contains 1600 mg of methacholine chloride powder which is to be reconstituted with 0.9% sodium chloride injection or 0.9% sodium chloride injection containing 0.4% phenol (pH 7.0). See DOSAGE AND ADMINISTRATION for dilution procedures, concentrations and schedule of administration.

Chemically, methacholine chloride (the active ingredient) is 1-propanaminium, 2-(acetyloxy)­N,N,N, - trimethyl,-chloride. It is a white to practically white deliquescent compound, soluble in water. Methacholine chloride has an empirical formula of C8H18ClN02, a calculated molecular weight of 195.69, and the following structural formula:

Methacholine formula

Hepatitis-sode Manufacturers

  • Synergy Formulas, Inc.
    Hepatitis-sode (Triticum Aestivum, Berberis Vulgaris, Chelidonium Majus, Taraxacum Officinale, Arsenicum Album, Glutathione, Hepar Suis, Lymph (Suis), Phosphoricum Acidum, Spleen (Suis), Chelone Glabra, Germanium Sesquioxide, Hepatitis A Nosode, Hepatitis C Nosode, Hepatitis B Nosode) Liquid [Synergy Formulas, Inc.]

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