FDA records indicate that there are no current recalls for this drug.
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Hydromorphone Hydrochloride Suppository Recall
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Questions & Answers
Side Effects & Adverse Reactions
Hydromorphone hydrochloride produces dose-related respiratory depression by acting directly on brain stem respiratory centers. Hydromorphone hydrochloride also affects centers that control respiratory rhythm, and may produce irregular and periodic breathing.
The respiratory depressant effects of narcotics and their capacity to elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury, other intracranial lesions or a preexisting increase in intracranial pressure. Furthermore, narcotics produce effects which may obscure the clinical course of patients with head injuries.
The administration of narcotics may obscure the diagnosis or clinical course of patients with acute abdominal conditions.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Hydromorphone hydrochloride is indicated for the relief of moderate to severe pain such as that due to:
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History
There is currently no drug history available for this drug.
Other Information
Hydromorphone hydrochloride (WARNING: May be habit forming), a hydrogenated ketone of morphine, is a narcotic analgesic. It is available in:
Suppositories (for rectal administration) containing:
- 3 mg hydromorphone hydrochloride in a cocoa butter base with silicone dioxide.
The structural formula of hydromorphone hydrochloride is:

M.W. 321.8
Sources
Hydromorphone Hydrochloride Suppository Manufacturers
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Paddock Laboratories, Llc
Hydromorphone Hydrochloride Suppository | Paddock Laboratories, Llc
Hydromorphone Hydrochloride Suppositories (3 mg) may provide longer duration of relief which could obviate additional medication during the sleeping hours. The usual adult dose is one (1) suppository inserted rectally every 6 to 8 hours or as directed by physician.
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