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Questions & Answers
Side Effects & Adverse Reactions
HUMAN WARNINGS:
Not for use in humans. Keep this and all other drugs out of reach of children.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
There is currently no usage information available for this product. We apologize for any inconvenience.
History
There is currently no drug history available for this drug.
Other Information
DESCRIPTION:
LEGEND Injectable Solution is a clear, colorless solution of low viscosity. LEGEND Injectable Solution is pyrogen free, sterile and does not contain a preservative. It is administered by intravenous or intra-articular injection.
Hyaluronic acid, the conjugate acid of hyaluronate sodium, is extracted from the capsule of Streptococcus spp. and purified, resulting in a form which is essentially free of protein and nucleic acids.
LEGEND Injectable Solution is supplied in 2 mL (20 mg) vials. Each mL contains 10 mg hyaluronate sodium, 8.5 mg sodium chloride, 0.223 mg sodium phosphate dibasic, and 0.04 mg sodium phosphate monobasic. The pH is adjusted to between 6.5 and 8.0 with sodium hydroxide or hydrochloric acid.
Sources
Legend Manufacturers
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Merial, Inc.
![Legend (Hyaluronate Sodium) Injection, Solution [Merial, Inc.]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Legend | Merial, Inc.
DOSAGE AND ADMINISTRATION:
Intravenously-4 mL (40 mg), Intra-articular- 2 mL (20 mg) in the carpus or fetlock. Treatment may be repeated at weekly intervals for a total of three treatments.
Strict aseptic technique should be observed when administering by intra-articular injection. As with any intra-articular procedure, proper injection site disinfection and animal restraint are important. Excess joint fluid should be aseptically removed prior to injection. Care should be taken to avoid scratching the cartilage surface with the tip of the injection needle. Diffuse swelling lasting 24 to 48 hours may result from movement of the needle while in the joint space.
For intravenous administration, use aseptic technique and inject slowly into the jugular vein.
Horses should be given stall rest after treatment before gradually resuming normal activity.
Discard any unused portion of the drug and the empty vial after opening.
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Merial, Inc.
Legend | Merial, Inc.
DOSAGE AND ADMINISTRATION:
4 mL (40 mg) injected intravenously. Treatment may be repeated at weekly intervals for a total of three treatments.
Use aseptic technique and inject slowly into the jugular vein.
Horses should be given stall rest after treatment before gradually resuming normal activity.
Discard any unused portion of the drug and empty vial after opening.
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Bayer Healthcare Llc Animal Health Division
Legend | Bayer Healthcare Llc Animal Health Division
Intravenously-4 mL (40 mg), Intra-articular- 2 mL (20 mg) in the carpus or fetlock. Treatment may be repeated at weekly intervals for a total of three treatments.
Strict aseptic technique should be observed when administering by intra-articular injection. As with any intra-articular procedure, proper injection site disinfection and animal restraint are important. Excess joint fluid should be aseptically removed prior to injection. Care should be taken to avoid scratching the cartilage surface with the tip of the injection needle. Diffuse swelling lasting 24 to 48 hours may result from movement of the needle while in the joint space.
For intravenous administration, use aseptic technique and inject slowly into the jugular vein.
Horses should be given stall rest after treatment before gradually resuming normal activity.
Discard any unused portion of the drug and the empty vial after opening.
-
Bayer Healthcare Llc Animal Health Division
Legend | Bayer Healthcare Llc Animal Health Division
4 mL (40 mg) injected intravenously. Treatment may be repeated at weekly intervals for a total of three treatments.
Use aseptic technique and inject slowly into the jugular vein.
Horses should be given stall rest after treatment before gradually resuming normal activity.
Discard any unused portion of the drug and empty vial after opening.
-
Bayer Healthcare Llc Animal Health Division
Legend | Bayer Healthcare Llc Animal Health Division
4 mL (40 mg) injected intravenously. Treatment may be repeated at weekly intervals for a total of three treatments.
Use aseptic technique and inject slowly into the jugular vein.
Horses should be given stall rest after treatment before gradually resuming normal activity.
![Legend (Hyaluronate Sodium) Injection, Solution [Merial, Inc.]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=6d0866c3-e288-47b2-89d3-39a490a6ff0e&name=legend-01.jpg)
![Legend (Hyaluronate Sodium) Injection, Solution [Bayer Healthcare Llc Animal Health Division]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=5d39026b-d653-434f-bad2-29433894c10e&name=7b6faf84-5a59-4385-9071-4d166177832e-01.jpg)
![Legend (Hyaluronate Sodium) Injection, Solution [Bayer Healthcare Llc Animal Health Division]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=27817b26-d143-4a5f-b158-7d080be07ff1&name=762f99d5-54aa-4afc-a1b4-46b2b6f01b38-01.jpg)
![Legend (Hyaluronate Sodium) Injection, Solution [Bayer Healthcare Llc Animal Health Division]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=87988a76-f3ec-49e8-b46e-9a7ada6628e7&name=02368369-371e-4195-a76a-7cf93fa381d4-01.jpg)
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