Marquis Antiprotozoal
Loading...Marquis Antiprotozoal Recall
Get an alert when a recall is issued.
Questions & Answers
Side Effects & Adverse Reactions
WARNING: For use in animals only. Do not use in horses intended for human consumption. Not for human use. Keep out of the reach of children.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
There is currently no usage information available for this product. We apologize for any inconvenience.
History
There is currently no drug history available for this drug.
Other Information
DESCRIPTION: MARQUIS® (15% w/w ponazuril) Antiprotozoal Oral Paste is supplied in a ready-to-use syringe containing 127 grams of paste. Each gram of paste contains 150 mg of ponazuril (15% w/w). MARQUIS is designed to be delivered as an orally administered paste.
Each syringe barrel of MARQUIS contains enough paste to treat one (1) 1,200 lb (544 kg) horse for seven (7) days, at a dose rate of 5 mg/kg (2.27 mg/lb) body weight or to treat one 1,200 lb (544 kg) horse with a single loading dose of 15 mg/kg (6.81 mg/lb) body weight and for four days subsequently at a rate of 5 mg/kg (2.27 mg/lb) body weight. The plunger contains a dosage ring calibrated for a dose rate of 5 mg/kg (2.27 mg/lb) body weight and marked for horse weight from 600 to 1,200 lbs (272 to 544 kg). The syringe barrel is packaged with a reusable plunger. The syringe barrels are packaged in units of four with four reusable plungers and in single syringe units with one reusable plunger.
Ponazuril is an anticoccidial (antiprotozoal) compound with activity against several genera of the phylum Apicomplexa.
Sources
Marquis Antiprotozoal Manufacturers
-
Merial, Inc.
![Marquis Antiprotozoal (Ponazuril) Paste [Merial, Inc.]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Marquis Antiprotozoal | Merial, Inc.
DOSAGE: Administer MARQUIS at a dose of 15 mg/kg (6.81 mg/lb) body weight as a loading dose for the first dose only. The loading dose is followed by a maintenance dose of 5 mg/kg (2.27 mg/lb) body weight once daily for a period of 27 additional days.
Day 1: Administer a loading dose of 15 mg/kg (three times the maintenance dose) once by mouth. Because the dosage ring is calibrated by weight for the maintenance dose (5mg/kg), adjust the dosage ring to the appropriate weight and administer this 5 mg/kg dose orally, three consecutive times for a total dose of 15 mg/kg.
Day 2 through 28: Administer the maintenance dose of 5 mg/kg once daily by mouth.
ADMINISTRATION:
Paste syringe assembly:
Before administration, the syringe barrel and plunger require assembly. Ensure plunger is clean and dry. Step 1. End cap must be on syringe barrel when inserting plunger. Step 2. Carefully insert reusable plunger into base of syringe barrel until it snaps into place, then remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Step 3. Return end cap to tip of paste syringe. Administering MARQUIS to the horse: NOTE: The paste syringe is a multi-dose package. Ensure that the correct dose is administered with each use. For the first dose only, complete steps 3 through 6 three times, then continue with steps 7 and 8. Step 1. Remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Return end cap to tip of paste syringe. Step 2. Determine weight of horse and ensure the horse's mouth contains no feed. Step 3. To measure dose, dosage ring collar and barrel collar should be flush. Hold plunger and rotate dosage ring with the other hand to the weight of the horse. Step 4. Remove end cap from tip of syringe barrel. Step 5. The selected dose of paste should be deposited onto the back and top of the horse's tongue. Introduce tip of paste syringe into the side of the horse's mouth at the space between the front (incisor) and back (molar) teeth. Deposit paste on the horse's tongue by depressing the plunger of the syringe as far as the dose ring permits. Remove tip of syringe from horse's mouth. Step 6. To aid swallowing of paste, immediately raise horse's head for a few seconds after dosing. Step 7. Clean the tip of the syringe with a clean disposable towel and return end cap to tip of syringe barrel. Step 8. For the next daily dose, repeat steps 1-7. NOTE: At the end of the prescribed treatment period, partially used syringes should be discarded.
Login To Your Free Account