Moviprep

Moviprep Manufacturers

• Physicians Total Care, Inc.
  

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  Moviprep | Physicians Total Care, Inc.

  

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  The MoviPrep dose for colon cleansing for adult patients is 2 liters (approximately 64 ounces) of MoviPrep solution (with 1 additional liter of clear fluids) taken orally prior to the colonoscopy in one of the following ways:

  
  Split-dose MoviPrep regimen:  The evening before the colonoscopy, take the first liter of MoviPrep solution over one hour (one 8 ounce glass every 15 minutes) and then drink 0.5 liters (approximately 16 ounces) of clear fluid.  Then, on the morning of the colonoscopy, take the second liter of MoviPrep solution over one hour and then drink 0.5 liters of clear liquid at least one hour prior to the start of the colonoscopy; or Evening only (Full-dose) MoviPrep regimen:  Around 6 PM in the evening before the colonoscopy, take the first liter of MoviPrep solution over one hour (one 8 ounce glass every 15 minutes) and then about 1.5 hours later take the second liter of MoviPrep solution over one hour.  In addition, take 1 liter (approximately 32 ounces) of additional clear liquid during the evening before the colonoscopy.
  

  Preparation of the MoviPrep solution:

  MoviPrep solution is prepared by emptying the contents of 1 pouch A and 1 pouch B into a suitable glass container (or the container provided) and adding to the container 1 liter of lukewarm water.  Mix the solution to ensure that the ingredients are completely dissolved.  If the patient prefers, the MoviPrep solution can be refrigerated prior to drinking. The reconstituted solution should be used within 24 hours.

  
  

  After consumption of the first liter of MoviPrep solution, the above mixing procedure should be repeated with the second pouch A and pouch B to reconstitute the second liter of the MoviPrep solution.

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• Salix Pharmaceuticals, Inc.
  

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  Moviprep | Salix Pharmaceuticals, Inc.

  

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  2.1. Dosing Overview

  There are two possible dosing regimens.  Each regimen requires different dosing times:

  Split-dose (2-Day) [see Dosage and Administration (2.2)] Evening only (1-Day) [see Dosage and Administration (2.3)]

  Both MoviPrep dosing regimens require administration of MoviPrep using the mixing container provided to dilute powder for oral solution (contents of Pouch A and B) with water to the Fill line. Preparation of MoviPrep solution (the contents of one Pouch A and one Pouch B) occurs twice in each dosing regimen. Additional fluids must be consumed in both dosing regimens [see Dosage and Administration (2.2, 2.3)]. Instruct patients to consume only clear liquids (no solid food) from the start of MoviPrep treatment until after the colonoscopy [see Warnings and Precautions (5.1)]. Additionally, instruct patients to not consume any clear liquids at least 2 hours before the colonoscopy.

  2.2. Split-dose (2-Day) Regimen (Preferred Method)

  The Split-Dose regimen is the preferred dosing method. Instruct patients to take two separate doses in conjunction with fluids, as follows:

  Dose 1 – Take this dose the evening before the colonoscopy (10 to 12 hours before Dose 2)

  1. Empty the contents of 1 pouch A and 1 pouch B into the container that comes with MoviPrep.

  2. Add lukewarm water to the Fill line on the container.

  3. Mix to completely dissolve the contents of pouch A and B into the lukewarm water.

  4. Drink one 8 oz. (ounce) glass (240 mL) every 15 minutes. Be sure to drink all of the solution. This should take about 1 hour.

  5. Fill the container with 16 oz. (two 8 oz. glasses) of clear liquid and drink all of this liquid before going to bed.

  Dose 2 – Take this dose the next morning, on the day of the colonoscopy (start at least 3 ½ hours prior to colonoscopy)

  1. Repeat steps 1 through 4 from Dose 1 of the Split-dose (2-Day) instructions.

  2. Fill the container with 16 oz. (two 8 oz. glasses) of clear liquid and drink all of this liquid at least 2 hours before the colonoscopy.

  3. Drink only clear liquids up to 2 hours before the colonoscopy or as prescribed by your healthcare provider. Then stop drinking liquids until after the colonoscopy.

  2.3. Evening only (1-Day) Regimen (Alternative Method)

  The Day-Before regimen is the alternative dosing method for patients for whom the Split-Dosing regimen is inappropriate. Instruct patients to take two separate doses in conjunction with fluids as follows:

  Dose 1 – Take this dose at least 3 ½ hours before bedtime the evening before the colonoscopy:

  1. Empty the contents of 1 pouch A and 1 pouch B into the container that comes with MoviPrep.

  2. Add lukewarm water to the Fill Line on the container.

  3. Mix to completely dissolve the contents of pouch A and B into the lukewarm water.

  4. Drink one 8 oz. (ounce) glass (240 mL) every 15 minutes. Be sure to drink all of the solution. This should take about 1 hour.

  Dose 2 – Take Dose 2 about 1 ½ hours after starting Dose 1 on the evening before the colonoscopy:

  1. Repeat Steps 1 through 4 from Dose 1 of the Evening only (1-Day) instructions.

  2. After you complete step 1 through 4, fill the container again to the Fill Line with clear liquid and drink all of this liquid before going to bed.

  3. Drink only clear liquids up to 2 hours before the colonoscopy or as prescribed by your healthcare provider. Then stop drinking liquids until after the colonoscopy.

  Additional Information:

  MoviPrep solution may be refrigerated before drinking. Keep the mixed solution in an upright position and store in the refrigerator. MoviPrep should be taken within 24 hours after it is mixed in water. Do not add other ingredients to the MoviPrep solution.

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