Neo-polycin
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Questions & Answers
Side Effects & Adverse Reactions
NOT FOR INJECTION INTO THE EYE. Neomycin and polymyxin B sulfates and bacitracin zinc ophthalmic ointment should never be directly introduced into the anterior chamber of the eye. Ophthalmic ointments may retard corneal wound healing. Topical antibiotics, particularly neomycin sulfate, may cause cutaneous sensitization. A precise incidence of hypersensitivity reactions (primarily skin rash) due to topical antibiotics is not known. The manifestations of sensitization to topical antibiotics are usually itching, reddening, and edema of the conjunctiva and eyelid. A sensitization reaction may manifest simply as a failure to heal. During long-term use of topical antibiotic products, periodic examination for such signs is advisable, and the patient should be told to discontinue the product if they are observed. Symptoms usually subside quickly on withdrawing the medication. Applications of products containing these ingredients should be avoided for the patient thereafter (see PRECAUTIONS: General).
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Neo-PolycinTM Ophthalmic Ointment is indicated for the topical treatment of superficial infections of the external eye and its adnexa caused by susceptible bacteria. Such infections encompass conjunctivitis, keratitis, and keratoconjunctivitis, blepharitis and blepharoconjunctivitis.
History
There is currently no drug history available for this drug.
Other Information
Neomycin and polymyxin B sulfates and bacitracin zinc ophthalmic ointment is a sterile antimicrobial ointment for ophthalmic use. Each gram contains: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 10,000 polymyxin B units, bacitracin zinc equivalent to 400 bacitracin units in a white petrolatum and mineral oil base.
Neomycin sulfate is the sulfate salt of neomycin B and C, which are produced by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae). It has a potency equivalent of not less than 600 µg of neomycin standard per mg, calculated on an anhydrous basis. The structural formulae are:
Polymyxin B sulfate is the sulfate salt of polymyxin B1 and B2, which are produced by the growth of Bacillus polymyxa (Prazmowski) Migula (Fam. Bacillaceae). It has a potency of not less than 6,000 polymyxin B units per mg, calculated on an anhydrous basis. The structural formulae are:
Sources
Neo-polycin Manufacturers
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Fera Pharmaceuticals
![Neo-polycin (Neomycin And Polymyxin B Sulfates And Bacitracin Zinc) Ointment [Fera Pharmaceuticals]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Neo-polycin | Fera Pharmaceuticals
May be applied every 3 or 4 hours for 7 to 10 days, depending on the severity of the infection.
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Rebel Distributors Corp
Neo-polycin | Rebel Distributors Corp
May be applied every 3 or 4 hours for 7 to 10 days, depending on the severity of the infection.
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A-s Medication Solutions Llc
Neo-polycin | A-s Medication Solutions Llc
May be applied every 3 or 4 hours for 7 to 10 days, depending on the severity of the infection.
![Neo-polycin (Neomycin And Polymyxin B Sulfates And Bacitracin Zinc) Ointment [Rebel Distributors Corp]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=23764466-adbe-4c9c-be60-3b09458d634e&name=23764466-adbe-4c9c-be60-3b09458d634e-04.jpg)
![Neo-polycin (Neomycin And Polymyxin B Sulfates And Bacitracin Zinc) Ointment [A-s Medication Solutions Llc]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=1c57e9f5-07e9-4683-a16e-0f51053e9ecf&name=2391-0.jpg)
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