Paromomycin Sulfate
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Questions & Answers
Side Effects & Adverse Reactions
There is currently no warning information available for this product. We apologize for any inconvenience.
Legal Issues
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FDA Safety Alerts
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Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Paromomycin sulfate is indicated for intestinal amebiasis—acute and chronic (NOTE—It is not effective in extraintestinal amebiasis); management of hepatic coma—as adjunctive therapy.
History
There is currently no drug history available for this drug.
Other Information
Paromomycin sulfate is a broad spectrum antibiotic produced by Streptomyces riomosus var. paromomycinus. It is a white, amorphous, stable, water-soluble product. Paromomycin sulfate is designated chemically as O-2,6-Diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl(1→5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxystreptamine sulfate (salt). The molecular formula is C23H45N5O14 • xH2SO4, with a molecular weight of 615.64 (base). Its structural formula is:
Each capsule, for oral administration, contains paromomycin sulfate equivalent to 250 mg paromomycin. Each capsule also contains the following inactive ingredients: FD&C Green #3; FD&C Yellow #5 (tartrazine); gelatin, NF; and titanium dioxide, USP.
Sources
Paromomycin Sulfate Manufacturers
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Caraco Pharmaceutical Laboratories, Ltd.
![Paromomycin Sulfate Capsule [Caraco Pharmaceutical Laboratories, Ltd.]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Paromomycin Sulfate | Caraco Pharmaceutical Laboratories, Ltd.
Intestinal amebiasis: Adults and Children: Usual dose—25 to 35 mg/kg body weight daily, administered in three doses with meals, for five to ten days.
Management of hepatic coma: Adults: Usual dose—4 g daily in divided doses, given at regular intervals for five to six days.
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Heritage Pharmaceuticals Inc.
Paromomycin Sulfate | Heritage Pharmaceuticals Inc.
Intestinal amebiasis: Adults and Pediatric Patients: Usual dose—25 to 35 mg/kg body weight daily, administered in three doses with meals, for five to ten days.
Management of hepatic coma:
Adults: Usual dose—4 g daily in divided doses, given at regular intervals for five to six days.
![Paromomycin Sulfate Capsule [Heritage Pharmaceuticals Inc.]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=cc0f4113-e627-4caf-b2d4-95b4106e57f5&name=972af693-figure-01.jpg)
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