Penicillin Injectable
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Side Effects & Adverse Reactions
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Manufacturer Warnings
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FDA Labeling Changes
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Uses
INDICATIONS: Penicillin G Procaine is indicated for the treatment of:
1. Cattle and sheep - bacterial pneumonia (shipping fever) caused by Pasteurella multocida.
2. Swine - erysipelas caused by Erysipelothrix insidiosa.
3. Horses - strangles caused by Streptococcus equi.
DIRECTIONS FOR USE: Restricted Drug (California) - Use Only as Directed.
The suspension should be administered by deep intramuscular injection within the fleshy muscles of the hip, rump, round or thigh, or into the neck, changing the site for each injection. Do not inject subcutaneously, into a blood vessel, or near a major nerve.
Use a 16 or 18 gauge needle, 1.5 inches long. The needle and syringe should be washed thoroughly before use. The needle and syringe should then be sterilized by placing in boiling water for 15 to 20 minutes.
The injection site should be washed with soap and water and painted with a germicide such as tincture of iodine or 70% alcohol. The product should then be administered by using the following procedure:
1. Warm the vial to room temperature and shake thoroughly to ensure uniform suspension.
2. Wipe the rubber stopper on top of the vial with a piece of absorbent cotton soaked in 70% alcohol.
3. Inject air into the vial for easier withdrawal.
4. After filling the syringe, make sure the needle is empty by pulling back the plunger of the syringe until a small air bubble appears. Then detach the needle from the syringe.
5. Insert the needle deep into the muscle, attach the syringe and withdraw the plunger slightly. If blood appears, withdraw the needle and insert it into a different location.
6. Inject the dose slowly. Do not massage the site of injection.
7. Not more than 10 mL should be injected into one location.
Daily treatment should be continued for at least 48 hours after temperature has returned to normal and all other signs of infection have subsided. Animals treated with Penicillin G Procaine Injectable Suspension should show noticeable improvement within 26 to 48 hours.
History
There is currently no drug history available for this drug.
Other Information
Description: Penicillin G Procaine Injectable Suspension is available in 100-mL, 250-mL and 500-mL multiple dose vials. Each mL contains: penicillin G potassium 300,000 units*, procaine hydrochloride 130.8 mg*, methylparaben 1.3 mg, propylparaben 0.2 mg, sodium citrate 10 mg, sodium carboxymethylcellulose 1 mg, povidone 5 mg, lecithin 6 mg, sodium formaldehyde sulfoxylate 0.2 mg, procaine hydrochloride 20 mg, and Water for Injection, q.s.
*Penicillin G Potassium and Procaine Hydrochloride react to form Penicillin G Procaine.
Sources
Penicillin Injectable Manufacturers
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Durvet
![Penicillin Injectable (Penicillin G Procaine) Injection, Suspension [Durvet]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Penicillin Injectable | Durvet
DOSAGE: The dosage of cattle, sheep, swine, and horses is 3000 units per pound of body weight, or 1.0 mL for each 100 pounds of body weight once daily. Treatment should not exceed 7 days in on-lactating dairy and beef cattle, sheep, swine, or 5 days in lactating dairy cattle. If no improvement is observed within 48 hours, consult your veterinarian.
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