Periochip Recall

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Questions & Answers

Side Effects & Adverse Reactions

There is currently no warning information available for this product. We apologize for any inconvenience.

Legal Issues

There is currently no legal information available for this drug.

FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.


PerioChip is indicated as an adjunct to scaling and root planing procedures for reduction of pocket depth in patients with adult periodontitis. PerioChip may be used as a part of a periodontal maintenance program, which includes good oral hygiene and scaling and root planing.


There is currently no drug history available for this drug.

Other Information

PerioChip® (chlorhexidine gluconate) is a small, orange-brown, rectangular chip (rounded at one end) for insertion into periodontal pockets. Each PerioChip weighs approximately 7.4 mg and contains 2.5 mg of chlorhexidine gluconate in a biodegradable matrix of hydrolyzed gelatin (cross-linked with glutaraldehyde). PerioChip also contains glycerin and purified water.

Chlorhexidine gluconate is an antimicrobial agent. Chemically, it is designated as 1,1’-hexamethylenebis [5-(p-chlorophenyl)biguanide] di-D-gluconate, and its molecular formula is C 22H 30Cl 2N 10.2C 6H 12O 7. The molecular weight is 897.8. The structural formula of chlorhexidine gluconate is:

Chlorhexidine gluconate structural formula

Periochip Manufacturers

  • Adrian Pharmaceuticals, Llc
    Periochip (Chlorhexidine Gluconate) Insert, Extended Release [Adrian Pharmaceuticals, Llc]
  • Dexcel Pharma Technologies Ltd.
    Periochip (Chlorhexidine Gluconate) Insert, Extended Release [Dexcel Pharma Technologies Ltd.]

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