Pyrantel
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Questions & Answers
Side Effects & Adverse Reactions
WARNING: Do not use in horses intended for human consumption.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
INDICATIONS: For removal and control of mature infections of large strongyles (Strongylus vulgaris, S. edentatus, S. equinus); small strongyles; pinworms (Oxyuris equi); and large roundworms (Parascaris equorum) in horses and ponies.
Consult your veterinarian for asistance in the diagnosis, treatment, and control of parasitism.
History
There is currently no drug history available for this drug.
Other Information
DESCRIPTION: Pyrantel Paste (Pyrantel pamoate) is a pale yellow to buff paste containing 43.9% w/w pyrantel pamoate in an inert vehicle. Each syringe contains 3.6 grams pyrantel base in 23.6 grams paste. Each milliliter contains 171 milligram Pyrantel base as pyrantel pamoate.
READ ENTIRE DIRECTIONS CAREFULLY BEFORE USING THIS PRODUCT.
COMPOSITION: Pyrantel pamoate is a compound belonging to a family classified chemically as tetrahydropyrimidines. It is a yellow, water insoluble crystalline salt of the tetrahydropyrimidine base and pamoic acid containing 34.7% base activity.
CHEMICAL STRUCTURE:
CHEMICAL NAME:
(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)-vinyl]-pyrimidine 4,4' methylenebis [3-hydroxy-2 naphthoate] (1:1)
Sources
Pyrantel Manufacturers
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Durvet,inc
![Pyrantel (Pyrantel Pamoate) Paste [Durvet,inc]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Pyrantel | Durvet,inc
DOSAGE AND TREATMENT: Pyrantel Paste (pyrantel pamoate) is to be adminitered as a single oral dose of 3 milligrams pytantel base per pound of body weight. The syringe has four weight mark increments. Each weight mark indicated the recommended dose for 300 pounds of body weight.
Dosage:
Body Weight Range
Quantity
mg Pyrantel Base
up to 300 lb
¼ syringe
900 mg
301 to 600 lb
½ syringe
1800 mg
601 to 900 lb
¾ syringe
2700 mg
901 to 1200 lb
1 full syringe
3600 mg
NOTE: Position ring-gauge over appropriate mark on plunger.
For maximum control of parasitism it is recommended that foals(2-8 months of age) be dosed every 4 weeks. To minimize the potential source of infection that the mare may pose to the foal, the mare should be treated 1 month prior to anticipated foaling date followed by re-treatment 10 days to 2 weeks after birth of the foal. Horses and ponies over 8 months of age should be routinely dosed every 6 weeks.
It is recommended that severely debilitated animals not be treated with this preparation.
ADMINISTRATION:
After removing the cap, the paste should be deposited on the dorsum of the tongue. Introduce the nozzle end of the syringe at the corner of the mouth. Direct the syringe backward and depress the plunger to deposit the paste onto the tongue. Given in this manner, it is unlikely that rejection of the paste will occur. Raising the horse’s head sometimes assists in the swallowing process. When only part of the paste has been used, replace the cap on the syringe nozzle.
EFFICACY: Critical (worm count) studies in horses demonstrated that pyrantel pamoate administered at the recommended dosage was efficacious against mature infection of Strongylus vulgaris (>90%), S.edentatus (69%), S.equinus (>90%), Oxyuris equi (81%), Parascaris equorum (>90%), and small strongyles (>90%).
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