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Questions & Answers

Side Effects & Adverse Reactions

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Legal Issues

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FDA Safety Alerts

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Manufacturer Warnings

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FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.


Mesna injection is indicated as a prophylactic agent in reducing the incidence of ifosfamide-induced hemorrhagic cystitis.

Limitation of Use:
Mesna injection is not indicated to reduce the risk of hematuria due to other pathological conditions such as thrombocytopenia.


There is currently no drug history available for this drug.

Other Information

Mesna Injection is a detoxifying agent to inhibit the hemorrhagic cystitis induced by ifosfamide.  The active ingredient, mesna, is a synthetic sulfhydryl compound designated as sodium-2-mercaptoethane sulfonate with a molecular formula of C2H5NaO3S2 and a molecular weight of 164.18.  Its structural formula is as follows:


Mesna injection is a sterile, nonpyrogenic, aqueous solution of clear and colorless appearance in clear glass multiple dose vials for intravenous administration.  Mesna injection contains 100 mg/mL mesna, 0.25 mg/mL edetate disodium and sodium hydroxide for pH adjustment.  Mesna injection multiple dose vials also contain 10.4 mg/mL of benzyl alcohol as a preservative.  The solution has a pH range of 6.5 to 8.5.

Rejuvesol Manufacturers

  • Citra Labs Llc
    Rejuvesol (Sodium Pyruvate, Inosine, Adenine, Sodium Phosphate, Dibasic, And Sodium Phosphate, Monobasic, Monohydrate) Solution [Citra Labs Llc]

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