FDA records indicate that there are no current recalls for this drug.
Are you a medical professional?
Trending Topics
Rompe Pecho Cf Recall
Get an alert when a recall is issued.
Questions & Answers
Side Effects & Adverse Reactions
There is currently no warning information available for this product. We apologize for any inconvenience.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Memantine hydrochloride is indicated for the treatment of moderate to severe dementia of the Alzheimer’s type.
History
There is currently no drug history available for this drug.
Other Information
Memantine hydrochloride is an orally active NMDA receptor antagonist. The chemical name for memantine hydrochloride is 1-amino-3,5-dimethyladamantane hydrochloride with the following structural formula:
The molecular formula is C12H21N•HCl and the molecular weight is 215.76.
Memantine HCl occurs as a fine white to off-white powder and is soluble in water. Memantine hydrochloride is available as tablets. Memantine hydrochloride is available for oral administration as capsule-shaped, film-coated tablets containing 5 mg and 10 mg of memantine hydrochloride. The tablets also contain the following inactive ingredients: microcrystalline cellulose, talc, croscarmellose sodium, colloidal silicon dioxide, magnesium stearate and anhydrous lactose. In addition the following inactive ingredients are also present as components of the film coat: hypromellose, titanium dioxide, macrogol/polyethylene glycol 4000, FD&C yellow #6, iron oxide red and FD&C blue #2 (5 mg tablets), and hypromellose, titanium dioxide, macrogol/polyethylene glycol 4000 and FD&C blue #2 (10 mg tablets).
Sources
Rompe Pecho Cf Manufacturers
-
Efficient Laboratories Inc
Rompe Pecho Cf | Orchid Chemicals & Pharmaceuticals Limited
The dosage of memantine hydrochloride shown to be effective in controlled clinical trials is 20 mg/day.
The recommended starting dose of memantine hydrochloride is 5 mg once daily. The recommended target dose is 20 mg/day. The dose should be increased in 5 mg increments to 10 mg/day (5 mg twice a day), 15 mg/day (5 mg and 10 mg as separate doses), and 20 mg/day (10 mg twice a day). The minimum recommended interval between dose increases is one week.
Memantine hydrochloride can be taken with or without food.
Doses in Special PopulationsA target dose of 5 mg BID is recommended in patients with severe renal impairment (creatinine clearance of 5 to 29 mL/min based on the Cockroft-Gault equation):
For males: CLcr = [140-age (years)] · Weight (kg)/[72 · serum creatinine (mg/dL)]
For females: CLcr = 0.85 · [140-age (years)] · Weight (kg)/[72 · serum creatinine (mg/dL)]
Login To Your Free Account