FDA records indicate that there are no current recalls for this drug.
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Questions & Answers
Side Effects & Adverse Reactions
This product may cause drowsiness or blurred vision. Patients taking this product should be warned not to
engage in activities requiring mental alertness such as operating a motor vehicle or other machinery or to perform
hazardous tasks while taking this drug.
Do not exceed recommended dosage.
Heat prostration can occur with the use of scopolamine methyl nitrate when the environmental temperature is high.
Diarrhea may be an early symptom of incomplete intestinal obstruction, especially in patients with ileostomy or
colostomy; in this instance, use of scopolamine methyl nitrate would be inappropriate and possibly harmful.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
This product is indicated for the temporary relief of symptoms associated with seasonal and
perennial allergic and non-allergic rhinitis, and sinusitis.Chlorpheniramine Maleate temporarily relieves runny nose
and reduces sneezing, itching of the nose or throat, and itchy,watery eyes due to hay fever or other upper respiratory
allergies. Scopolamine Methyl Nitrate further augments the anti-secretory activity of this product.
History
There is currently no drug history available for this drug.
Other Information
Each teaspoonful (5 mL) for oral administration contains:
Chlorpheniramine Maleate ...................................... 4 mg
Scopolamine Methyl Nitrate .............................. 1.25 mg
INACTIVE INGREDIENTS: Citric Acid, Grape flavor, Glycerin, Propylene Glycol, Purified Water, Sodium Citrate, Sodium
Saccharin, and Sorbitol.
RYNEZE® LIQUID contains ingredients from the following classes: antihistamine, and anticholinergic.
Chlorpheniramine Maleate is an antihistamine with the chemical name: 2-Pyridinepropanamine, γ-(4-chlorphenyl)-
N,N-dimethyl-, (Z)-2-butenedioate (1:1), and has the following chemical structure:
Scopolamine Methyl Nitrate is an anticholinergic belldonna alkaloid derivative with the chemical name:
[7(s)-(α,2β,4β,5α,7β,)]–7–(3–hydroxy–1-oxo – 2- Phenylpropoxy)-9, 9-dimethyl–3-oxa– 9-azoniatricyclo
[3.3.1.0 2,4] nonane nitrate.It has the following chemical structure:
Sources
Ryneze Manufacturers
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Sj Pharmaceuticals, Llc
Ryneze | Sj Pharmaceuticals, Llc
Adults and children 12 years of age and older:
1 teaspoonful (5 mL) every 4 to 6 hours, not to exceed 6 teaspoonfuls in 24 hours.
Children 6 to under 12 years of age:
½ teaspoonful (2.5 mL) every 4 to 6 hours, not to exceed 3 teaspoonfuls in 24 hours.
RYNEZE® LIQUID is not recommended for children under 6 years of age.
Note:Geriatric patients may be more sensitive to the effects of the usual adult dose. Adjust adult dose accordingly.
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