Salicylic Acid

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Salicylic Acid Recall

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Side Effects & Adverse Reactions

For external use only.

Flammable

keep away from fire and flame

Do not use

on moles, birth marks and warts with hair growing from them
on mucous membranes such as nose, anus, genitals and lips
on irritated, infected or reddened skin
on genital warts and warts on the face

When using this product

if product gets into the eyes, flush with water for 15 minutes
avoid inhaling vapors

Ask a Doctor

If discomforts persists see your doctor or podiatrist.

Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center right away.

Do not use

on moles, birth marks and warts with hair growing from them
on mucous membranes such as nose, anus, genitals and lips
on irritated, infected or reddened skin
on genital warts and warts on the face

Ask a Doctor

If discomforts persists see your doctor or podiatrist.

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Legal Issues

There is currently no legal information available for this drug.

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FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

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Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

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FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.

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Uses

for the removal of common and plantar warts. The common wart is easily recognized by the rough 'cauliflower-like' appearance of the surface.
Plantar wart is recognized by its location only on the bottom of the foot, its tenderness and the interruption of the footprint pattern.

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History

There is currently no drug history available for this drug.

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Other Information

There are no additional details available for this product.

Sources

Salicylic Acid Manufacturers

Meijer Distribution Inc

Salicylic Acid | Meijer Distribution Inc

after washing affected area, soak wart in for 5 minutes in comfortably warm water dry area thoroughly gently squeeze a drop of gel from tube and apply to wart. Apply one drop at a time to sufficiently cover each wart let dry repeat this procedure once or twice daily (until wart is removed) for up to 12 weeks

No Recall
Topco Associates Llc

Salicylic Acid | Topco Associates Llc

wash affected area and dry area thoroughly if necessary, cut medicated patch to fit corn apply adhesive side down of medicated patch onto corn cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 5 minutes to assist in removal

No Recall
Topco Associates Llc

Salicylic Acid | Topco Associates Llc

wash affected area and dry thoroughly if necessary, cut medicated patch to fit callus apply adhesive side down of medicated patch onto callus cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until callus is removed) may soak callus in warm water for 5 minutes to assist in removal

No Recall
Topco Associates Llc

Salicylic Acid | Topco Associates Llc

wash affected area and dry thoroughly apply one drop at a time with applicator, to sufficiently cover each corn/callus; let dry use cushions with hole centered over corn or callus to relieve pressure (additional cushions may be purchased separately) repeat this procedure once or twice daily as needed for up to 14 days (until corn/callus is removed)

No Recall
Premier Value

Salicylic Acid | Cvs Pharmacy

• Adults and children 6 years of age and older: Instill 1 or 2 drops in the affected eye(s) up to 4 times daily. • Children under 6 years: ask a doctor

No Recall
Premier Value

Salicylic Acid | H And M Hennes And Mauritz Lp

Use as a normal foundation. Apply liberally 15 minutes before sun exposure. Children under 6 months: Ask a doctor. Reapply at least every 2 hours. Use a water resistant sunscreen if swimming or sweating.

No Recall
Premier Value

Salicylic Acid | Topco Associates Llc

• this product does not contain directions or complete warnings for adult use • do not give more than directed (see overdose warning) • shake well before using • mL = milliliter • find right dose on chart. If possible, use weight to dose; otherwise, use age. • push air out of syringe. Insert syringe tip into bottle opening. • flip bottle upside down. Pull yellow part of syringe to the first dose line and then push product back into bottle. • pull yellow part of syringe until it reaches and stays at the correct dose • dispense liquid slowly into child’s mouth, toward inner cheek • repeat dose every 4 hours while symptoms last • do not give more than 5 times in 24 hours • replace cap tightly to maintain child resistance
Dosing Chart

Weight (lb)

Age (yr)

Dose (mL)*

under 24

under 2 years

ask a doctor

24-35

2-3 years

5 mL

* or as directed by a doctor

Attention: use only enclosed syringe specifically designed for use with this product. Do not use any other dosing device.

No Recall
Premier Value

Salicylic Acid | Chain Drug Consortium, Llc

Clean affected area apply a small amount on the area 1-3 times daily let dry a second coating may be applied for extra protection to remove, apply more Liquid Bandage and quickly wipe off finger nil polish remover may dissolve Liquid Bandage

No Recall
Premier Value

Salicylic Acid | Better Living Brands, Llc

drink a full glass of water with each dose adults and children 12 years and over: take 4 to 8 tablets every 4 hours not to exceed 48 tablets in 24 hours unless directed by a doctor children under 12 years: do not use unless directed by a doctor

No Recall
Premier Value

Salicylic Acid | Chain Drug Consortium, Llc

shake well before use
• do not exceed the maximum recommended daily dose in a 24 hour period
• dose may be taken once a day preferably at bedtime,
in divided doses, or as directed by a doctor
• follow each dosage with a full glass (8oz) of fluid

adults and children 2-4 tablespoons (30-60 mL)
12 years and over

children 6 years to 11 years 1-2 tablespoons (15-30 mL)

children under 6 years ask a doctor

No Recall
Premier Value

Salicylic Acid | Hyland's, Inc.

Children under 3 years of age
Dissolve 2 to 3 tablets on tongue 4 times daily.
If you prefer, tablets may be dissolved in a teaspoon of water and then given to the child. If the child is restless or wakeful, dissolve 2 tablets on tongue every hour for up to 6 doses. Teething Tablets are very soft and dissolve almost instantly in the mouth. Please note: if your child has been crying or upset, your child may fall asleep after using this product because the pain has been relieved and your child can rest.

No Recall
Walgreens Company

Salicylic Acid | Walgreens Company

wash affected area and dry area thoroughly if necessary, cut medicated patch to fit corn apply adhesive side down of medicated patch onto corn cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 5 minutes to assist in removal

No Recall
Cvs

Salicylic Acid | Cvs

Directions
- Cleanse skin thoroughly before
applying medication
- cover the entire affected area with
a thin layer one to two times daily
- because excessive drying of the
skin may occur, start with one
application daily, then gradually
increase to two or three times
daily if needed or as directed by
a doctor
- if bothersome dryness or peeling
occurs, reduce application to
once a day or every other day

No Recall
Exact-rx, Inc.

Salicylic Acid | Exact-rx, Inc.

The preferable method of use is to apply SA 6% thoroughly to the affected area and to cover the treated area at night after washing and before retiring. Preferably, the skin should be hydrated for a least five minutes prior to application. The medication is washed off in the morning and if excessive drying and/or irritation is observed, a bland cream or lotion may be applied. Once clearing is apparent, the occasional use of SA 6% will usually maintain the remission. In those areas where occlusion is difficult or impossible, application may be made more frequently; hydration by wet packs or baths prior to application apparently enhances the effect. (See WARNINGS.) Unless hands are being treated, hands should be rinsed thoroughly after application. Excessive repeated application of SA 6% will not necessarily increase its therapeutic benefit, but could result in increased local intolerance and systemic adverse effects such as salicylism.

No Recall
Acella Pharmaceuticals, Llc

Salicylic Acid | Acella Pharmaceuticals, Llc

Prior to application of Salicylic Acid, 27.5% Wart Remover, soak wart in warm water for five minutes. Remove any loosened tissue by gently rubbing with a brush, wash cloth or emery board. Dry thoroughly. Using the brush applicator supplied, apply twice to entire wart surface, allowing the first application to dry before applying the second. Treatment should be once or twice a day and should continue as directed by physician. Be careful not to apply to surrounding skin.

Clinically visible improvement will normally occur during the first or second week of therapy. Maximum resolution may be expected after four to six weeks of use.

No Recall
Prugen, Inc.

Salicylic Acid | Prugen, Inc.

The preferable method of use is to apply 6% Salicylic  Acid Cream thoroughly to the affected area and to  cover the treated area at night after washing and  before retiring. Preferably, the skin should be  hydrated for at least five minutes prior to application. The medication is washed off in the morning and if  excessive drying and/or irritation is observed, a bland  cream or lotion may be applied. Once clearing is  apparent, the occasional use of Salicylic Acid 6%  Cream will usually maintain the remission. In those  areas where occlusion is difficult or impossible,  application may be made more frequently; hydration by wet packs or baths prior to application apparently  enhances the effect. (See WARNINGS.) Unless hands  are being treated, hands should be rinsed thoroughly  after application. Excessive repeated application of  Salicylic Acid 6% Cream will not necessarily increase  its therapeutic benefit, but could result in increased  local intolerance and systemic adverse effects such  as salicylism.

No Recall
Trinity Pharmaceuticals, Llc

Salicylic Acid | Trinity Pharmaceuticals, Llc

The preferable method of use is to apply Salicylic Acid 6% thoroughly to the affected area and to cover the treated area at night after washing and before retiring. Preferably, the skin should be hydrated for a least five minutes prior to application. The medication is washed off in the morning and if excessive drying and/or irritation is observed, a bland cream or lotion may be applied. Once clearing is apparent, the occasional use of Salicylic Acid 6% will usually maintain the remission. In those areas where occlusion is difficult or impossible, application may be made more frequently; hydration by wet packs or baths prior to application apparently enhances the effect. (See WARNINGS.) Unless hands are being treated, hands should be rinsed thoroughly after application. Excessive repeated application of Salicylic Acid 6% will not necessarily increase its therapeutic benefit, but could result in increased local intolerance and systemic adverse effects such as salicylism.

No Recall
Rochester Pharmaceuticals

Salicylic Acid | Rochester Pharmaceuticals

Prior to application of Salicylic Acid, 27.5% Wart Remover, soak wart in warm water for five minutes. Remove any loosened tissue by gently rubbing with a brush, wash cloth, emery board or pumice stone. Dry thoroughly. Using the brush applicator supplied, apply twice to entire wart surface, allowing the first application to dry before applying the second. Treatment should be once or twice a day and should continue as directed by physician. Be careful not to apply to surrounding skin. Clinically visible improvement will normally occur during the first or second week of therapy. Maximum resolution may be expected after four to six weeks of drug use.

No Recall
Rochester Pharmaceuticals

Salicylic Acid | Rochester Pharmaceuticals

Prior to application of Salicylic Acid, 26%, soak wart in warm water for five minutes. Remove any loosened tissue by gently rubbing with a brush, wash cloth or emery board. Dry thoroughly. Using the brush applicator supplied, apply twice to entire wart surface, allowing the first application to dry before applying the second. Treatment should be once or twice a day and should continue as directed by physician. Be careful not to apply to surrounding skin. Clinically visible improvement will normally occur during the first or second week of therapy. Maximum resolution may be expected after four to six weeks of drug use.

No Recall
Target Corporation

Salicylic Acid | Target Corporation

wash or soak the affected area and dry area thoroughly apply wart remover liquid with enclosed applicator, until wart is covered; then let dry reapply subsequent applications over existing application repeat this procedure once or twice daily until wart is completely removed, for up to 12 weeks

No Recall
Premier Brands Of America Inc.

Salicylic Acid | Premier Brands Of America Inc.

wash affected area: may soak wart in warm water for 5 minutes dry area thoroughly remove bandage strips by peeling backing off at slit adhere medicated patch directly over wart repeat this procedure every 48 hours as needed (until wart is removed) for up to 12 weeks

No Recall
Premier Brands Of America Inc.

Salicylic Acid | Premier Brands Of America Inc.

wash affected area, may soak wart in warm water for 5 minutes dry area thoroughly if necessary, cut medicated patch to fit wart apply adhesive side down of patch onto wartcover patch with pad to conceal area repeat this procedure every 48 hours as needed (until wart is removed) for up to 12 weeks

No Recall
Premier Brands Of America Inc.

Salicylic Acid | Premier Brands Of America Inc.

wash affected area: may soak corn in warm water for 5 minutes to assist in removal

dry area thoroughly

remove bandage strips by peeling backing off at slit

adhere medicated strip directly over corn

after 48 hours remove medicated bandage strip
repeat this procedure every 48 hours as needed (until wart is removed) for up to 12 weeks

No Recall
Premier Brands Of America Inc.

Salicylic Acid | Premier Brands Of America Inc.

wash affected area and dry area thoroughly if necessary, cut medicated patch to fit corn apply adhesive side down of medicated patch onto corn cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 5 minutes to assist in removal

No Recall
Premier Brands Of America Inc.

Salicylic Acid | Premier Brands Of America Inc.

wash affected area and dry area thoroughly if necessary, cut medicated patch to fit corn apply adhesive side down of medicated patch onto corn cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 5 minutes to assist in removal

No Recall
Premier Brands Of America Inc.

Salicylic Acid | Premier Brands Of America Inc.

wash affected area and dry thoroughly
if necessary, cut medicated patch to fit callus

apply adhesive side down of medicated patch onto callus

cover medicated patch with pad

after 48 hours, remove medicated patch

repeat procedure every 48 hours as needed for up to 14 days (until callus is removed)

may soak callus in warm water for 5 minutes to assist in removal
continued wearing of pad (without patch) will help prevent recurrence of calluses

No Recall
Premier Brands Of America Inc.

Salicylic Acid | Premier Brands Of America Inc.

wash affected area and dry area thoroughly if necessary, cut medicated patch to fit corn apply adhesive side down of medicated patch onto corn cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 5 minutes to assist in removal

No Recall
Premier Brands Of America Inc.

Salicylic Acid | Premier Brands Of America Inc.

wash affected area and dry thoroughly if necessary, cut medicated patch to fit callus apply adhesive side down of medicated patch onto callus cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until callus is removed) may soak callus in warm water for 5 minutes to assist in removal

No Recall
Sergeant’s Pet Care Products, Inc.

Salicylic Acid | Sun Pharmaceutical Industries, Inc.

Adults and Children over 10 years of age: Usual dose is one 100 mg or 200 mg capsule three times a day as needed for cough. If necessary to control cough, up to 600 mg daily in three divided doses may be given. Benzonatate Capsules should be swallowed whole. Benzonatate Capsules are not to be broken, chewed, dissolved, cut or crushed.

No Recall
Cardinal Health

Salicylic Acid | Cardinal Health

wash affected area and dry thoroughly apply one drop at a time with applicator, to sufficiently cover each corn/callus; let dry use cushions with hole centered over corn or callus to relieve pressure (additional cushions may be purchased separately) repeat this procedure once or twice daily as needed for up to 14 days (until corn/callus is removed)

No Recall
Cardinal Health

Salicylic Acid | Cardinal Health

wash affected area and dry thoroughly if necessary, cut medicated patch to fit corn apply adhesive side down of medicated patch onto corn cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 15 minutes to assist in removal

No Recall
Cardinal Health

Salicylic Acid | Cardinal Health

wash affected area: may soak wart in warm water for 5 minutes dry area thoroughly remove bandage strips by peeling backing off at slit adhere medicated patch directly over wart repeat this procedure every 48 hours as needed (until wart is removed) for up to 12 weeks

No Recall
Cardinal Health

Salicylic Acid | Cardinal Health

wash affected area and dry thoroughly if necessary, cut medicated patch to fit callus apply adhesive side down of medicated patch onto callus cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until callus is removed) may soak callus in warm water for 5 minutes to assist in removal continued wearing of pad (without patch) will help prevent recurrence of calluses

No Recall
Cardinal Health

Salicylic Acid | Cardinal Health

wash or soak the affected area, may soak wart in warm water for 5 minutes dry area thoroughly apply small amount of wart remover with applicator to sufficiently cover each wart let dry and repeat this procedure once or twice daily as needed until wart is removed for up to 12 weeks

No Recall
Cvs Pharmacy

Salicylic Acid | Cvs Pharmacy

wash affected area and dry thoroughly apply one drop at a time with applicator, to sufficiently cover each corn/callus; let dry use cushions with hole centered over corn or callus to relieve pressure (additional cushions may be purchased separately) repeat this procedure once or twice daily as needed for up to 14 days (until corn/callus is removed)

No Recall
Cvs Pharmacy

Salicylic Acid | Cvs Pharmacy

wash affected area and dry thoroughlyif necessary, cut medicated patch to fit callus apply adhesive side down of medicated patch onto callus cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until callus is removed) may soak callus in warm water for 5 minutes to assist in removal

No Recall
Cvs Pharmacy

Salicylic Acid | Cvs Pharmacy

wash affected area and dry area thoroughly if necessary, cut medicated patch to fit corn apply adhesive side down of medicated patch onto corn cover medicated patch with padafter 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 5 minutes to assist in removal

No Recall
Cvs Pharmacy

Salicylic Acid | Dza Brands Llc

• this product does not contain directions or complete warnings for adult use • do not give more than directed (see overdose warning) • shake well before using • mL = milliliter • find right dose on chart. If possible, use weight to dose; otherwise, use age. • push air out of syringe. Insert syringe tip into bottle opening. • flip bottle upside down. Pull yellow part of syringe to the first dose line and then push product back into bottle. • pull yellow part of syringe until it reaches and stays at the correct dose • dispense liquid slowly into child’s mouth, toward inner cheek • repeat dose every 4 hours while symptoms last • do not give more than 5 times in 24 hours • replace cap tightly to maintain child resistance
Dosing Chart

Weight (lb)

Age (yr)

Dose (mL)*

under 24

under 2 years

ask a doctor

24-35

2-3 years

5 mL

* or as directed by a doctor

Attention: use only enclosed syringe specifically designed for use with this product. Do not use any other dosing device.

No Recall
Cvs Pharmacy

Salicylic Acid | Cvs Pharmacy

wash affected area, may soak wart in warm water for 5 minutes dry area thoroughly if necessary, cut medicated patch to fit wart apply adhesive side down of patch onto wart cover patch with pad to conceal area repeat this procedure every 48 hours as needed (until wart is removed) for up to 12 weeks

No Recall
Cvs Pharmacy

Salicylic Acid | Cvs Pharmacy

wash affected area, may soak wart in warm water for 5 minutes dry area thoroughly if necessary, cut medicated patches to fit wart apply the adhesive side of patch onto wart cover patch with pads to conceal area repeat procedure every 48 hours as needed (until wart is removed) for up to 12 weeks

No Recall
Cvs Pharmacy

Salicylic Acid | Cvs Pharmacy

wash affected area: may soak wart in warm water for 5 minutes dry area thoroughly remove bandage strips by peeling backing off at slit adhere medicated patch directly over wart repeat this procedure every 48 hours as needed (until wart is removed) for up to 12 weeks

No Recall
Cvs Pharmacy

Salicylic Acid | Cvs Pharmacy

wash affected area and dry area thoroughly if necessary, cut medicated patch to fit callus apply adhesive side down of medicated patch onto callus cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 5 minutes to assist in removal

No Recall
Cvs Pharmacy

Salicylic Acid | Cvs Pharmacy

wash affected area and dry area thoroughly if necessary, cut medicated patch to fit corn apply adhesive side down of medicated patch onto corn cover medicated patch with cover after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 5 minutes to assist in removal

No Recall
Wal-mart Stores, Inc.

Salicylic Acid | Wal-mart Stores, Inc.

wash affected area and dry thoroughly apply one drop at a time with applicator, to sufficiently cover each corn/callus; let dry use cushions with hole centered over corn or callus to relieve pressure (additional cushions may be purchased separately) repeat this procedure once or twice daily as needed for up to 14 days (until corn/callus is removed)

No Recall
Cvs Pharmacy

Salicylic Acid | Cvs Pharmacy

after washing affected area may soak wart in warm water for 5 minutes dry area thoroughly remove cap from pen remove insert pin from the tip and discard twist and click pen until wart remover gel is dispensed onto the tip of the applicator. Initial use will require several rotations for the gel to load apply a small amount at a to sufficiently cover each wart let dry repeat this procedure once or twice daily (until wart is removed) for up to 12 weeks for storage, ensure applicator is free of excess gel before placing the cap back on keep outer package for complete Drug Facts information

No Recall
Walgreen Company

Salicylic Acid | Walgreen Company

wash affected area may soak wart in for 5 minutes dry area thoroughly remove cap from pen remove insert pin from the tip twist and click pen until wart remover gel is dispense onto the tip of the applicator. Initial use will require several rotations for the gel to load apply a small amount at a time with applicator to sufficiently cover each wart let dry repeat this procedure once or twice daily as needed (until wart is removed) for up to 12 weeks for storage ensure applicator is free of excess gel before placing the insert pin back into the tip

No Recall
Walgreen Company

Salicylic Acid | Mylan Institutional Llc

Vecuronium bromide for injection is for intravenous use only.

This drug should be administered by or under the supervision of experienced clinicians familiar with the use of neuromuscular blocking agents. Dosage must be individualized in each case. The dosage information which follows is derived from studies based upon units of drug per unit of body weight and is intended to serve as a guide only, especially regarding enhancement of neuromuscular blockade of vecuronium bromide by volatile anesthetics and by prior use of succinylcholine (see PRECAUTIONS, Drug Interactions).

To obtain maximum clinical benefits of vecuronium bromide and to minimize the possibility of overdosage, the monitoring of muscle twitch response to peripheral nerve stimulation is advised.

The recommended initial dose of vecuronium bromide is 0.08 to 0.1 mg/kg (1.4 to 1.75 times the ED90) given as an intravenous bolus injection. This dose can be expected to produce good or excellent non-emergency intubation conditions in 2.5 to 3 minutes after injection. Under balanced anesthesia, clinically required neuromuscular blockade lasts approximately 25 to 30 minutes, with recovery to 25% of control achieved approximately 25 to 40 minutes after injection and recovery to 95% of control achieved approximately 45 to 65 minutes after injection. In the presence of potent inhalation anesthetics, the neuromuscular blocking effect of vecuronium bromide is enhanced. If vecuronium bromide is first administered more than 5 minutes after the start of inhalation agent or when steady-state has been achieved, the initial vecuronium bromide dose may be reduced by approximately 15%, i.e., 0.06 to 0.085 mg/kg.

Prior administration of succinylcholine may enhance the neuromuscular blocking effect and duration of action of vecuronium bromide. If intubation is performed using succinylcholine, a reduction of initial dose of vecuronium bromide to 0.04 to 0.06 mg/kg with inhalation anesthesia and 0.05 to 0.06 mg/kg with balanced anesthesia may be required.

During prolonged surgical procedures, maintenance doses of 0.01 to 0.015 mg/kg of vecuronium bromide are recommended; after the initial vecuronium bromide injection, the first maintenance dose will generally be required within 25 to 40 minutes. However, clinical criteria should be used to determine the need for maintenance doses.

Since vecuronium bromide lacks clinically important cumulative effects, subsequent maintenance doses, if required, may be administered at relatively regular intervals for each patient, ranging approximately from 12 to 15 minutes under balanced anesthesia, slightly longer under inhalation agents. (If less frequent administration is desired, higher maintenance doses may be administered.)

Should there be reason for the selection of larger doses in individual patients, initial doses ranging from 0.15 mg/kg up to 0.28 mg/kg have been administered during surgery under halothane anesthesia without ill effects to the cardiovascular system being noted as long as ventilation is properly maintained (see CLINICAL PHARMACOLOGY, Pharmacokinetics).
Use by Continuous Infusion
After an intubating dose of 80 to 100 mcg/kg, a continuous infusion of 1 mcg/kg/min can be initiated approximately 20 to 40 minutes later. Infusion of vecuronium bromide should be initiated only after early evidence of spontaneous recovery from the bolus dose. Long-term intravenous infusion to support mechanical ventilation in the intensive care unit has not been studied sufficiently to support dosage recommendations. (See PRECAUTIONS, Long Term Use in ICU.)

The infusion of vecuronium bromide should be individualized for each patient. The rate of administration should be adjusted according to the patient's twitch response as determined by peripheral nerve stimulation. An initial rate of 1 mcg/kg/min is recommended, with the rate of the infusion adjusted thereafter to maintain a 90% suppression of twitch response. Average infusion rates may range from 0.8 to 1.2 mcg/kg/min.

Inhalation anesthetics, particularly enflurane and isoflurane may enhance the neuromuscular blocking action of nondepolarizing muscle relaxants. In the presence of steady state concentrations of enflurane or isoflurane, it may be necessary to reduce the rate of infusion 25 to 60 percent, 45 to 60 minutes after the intubating dose. Under halothane anesthesia it may not be necessary to reduce the rate of infusion.

Spontaneous recovery and reversal of neuromuscular blockade following discontinuation of vecuronium bromide infusion may be expected to proceed at rates comparable to that following a single bolus dose (see CLINICAL PHARMACOLOGY).

Infusion solutions of vecuronium bromide can be prepared by adding vecuronium bromide with an appropriate infusion solution such as Dextrose 5% Injection, Sodium Chloride 0.9% Injection, Dextrose 5% and Sodium Chloride 0.9% Injection, or Lactated Ringer's Injection.

Unused portions of infusion solutions should be discarded.

Infusion rates of vecuronium bromide can be individualized for each patient using the following table:
*10 mg of Vecuronium bromide in 100 mL solution
‡20 mg of Vecuronium bromide in 100 mL solution

Drug Delivery Rate
(mcg/kg/min)

Infusion Delivery Rate

(mL/kg/min)

0.1 mg/mL*

0.2 mg/mL‡

0.7

0.007

0.0035

0.8

0.008

0.0040

0.9

0.009

0.0045

1.0

0.010

0.0050

1.1

0.011

0.0055

1.2

0.012

0.0060

1.3

0.013

0.0065

The following table is a guideline for mL/min delivery for a solution of 0.1 mg/mL (10 mg in 100 mL) with an infusion pump.
VECURONIUM BROMIDE INFUSION RATE - mL/min NOTE: If a concentration of 0.2 mg/mL is used (20 mg in 100 mL), the rate should be decreased by one half.
Amount of Drug
mcg/kg/min

Patient Weight - kg

40

50

60

70

80

90

100

0.7

0.28

0.35

0.42

0.49

0.56

0.63

0.70

0.8

0.32

0.40

0.48

0.56

0.64

0.72

0.80

0.9

0.36

0.45

0.54

0.63

0.72

0.81

0.90

1.0

0.40

0.50

0.60

0.70

0.80

0.90

1.00

1.1

0.44

0.55

0.66

0.77

0.88

0.99

1.10

1.2

0.48

0.60

0.72

0.84

0.96

1.08

1.20

1.3

0.52

0.65

0.78

0.91

1.04

1.17

1.30
Use in Pediatrics
Pediatric patients (10 to 16 years of age) have approximately the same dosage requirements (mg/kg) as adults and may be managed the same way. Younger pediatric patients (1 to 10 years of age) may require a slightly higher initial dose and may also require supplementation slightly more often than adults.

Infants under 1 year of age but older than 7 weeks are moderately more sensitive to vecuronium bromide on a mg/kg basis than adults and take about 1 1/2 times as long to recover. See also subsection of PRECAUTIONS titled Pediatric Use. Information presently available does not permit recommendation on usage in pediatric patients less then 7 weeks of age (see PRECAUTIONS - Pediatric Use). There are insufficient data concerning continuous infusion of vecuronium in pediatric patients, therefore, no dosing recommendations can be made.
COMPATIBILITY
Vecuronium bromide is compatible in solution with:

Sodium Chloride 0.9% Injection

Dextrose 5% Injection

Sterile Water for Injection

Dextrose 5% in Sodium Chloride 0.9% Injection

Lactated Ringer's Injection

Use within 24 hours of mixing with the above solutions.

Vecuronium bromide is also compatible in solution with:

Bacteriostatic Water for Injection (NOT FOR USE IN NEWBORNS)

Use within 5 days of mixing with the above solution.

Reconstituted vecuronium bromide, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line.

After Reconstitution

See DOSAGE AND ADMINISTRATION-COMPATIBILITY for diluents compatible with Vecuronium Bromide for Injection.

Single-Dose Use

When reconstituted with compatible IV solutions not containing an antimicrobial preservative (e.g., Sterile Water for Injection), refrigerate and use within 24 hours. Discard unused portion.

Multi-Dose Use (NOT FOR USE IN NEWBORNS)

When reconstituted with bacteriostatic Water for Injection, use within 5 days. The reconstituted solution may be stored at room temperature or refrigerated.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

No Recall
Walgreen Company

Salicylic Acid | Walgreen Company

wash affected area and dry thoroughly apply one drop at a time with applicator, to sufficiently cover each corn/callus; let dry use cushions with hole centered over corn or callus to relieve pressure (additional cushions may be purchased separately) repeat this procedure once or twice daily as needed for up to 14 days (until corn/callus is removed)

No Recall
Walgreen Company

Salicylic Acid | Walgreen Company

wash affected area and dry area thoroughly if necessary, cut medicated patch to fit corn apply adhesive side down of medicated patch onto corn cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until corn is removed) may soak corn in warm water for 5 minutes to assist in removal

No Recall
Walgreen Company

Salicylic Acid | Walgreen Company

wash affected area and dry thoroughly if necessary, cut medicated patch to fit callus apply adhesive side down of medicated patch onto callus cover medicated patch with pad after 48 hours, remove medicated patch repeat procedure every 48 hours as needed for up to 14 days (until callus is removed) may soak callus in warm water for 5 minutes to assist in removal

No Recall
Chain Drug Marketing Association Inc.

Salicylic Acid | Chain Drug Marketing Association Inc.

wash affected area and dry thoroughly apply one drop at a time with applicator, to sufficiently cover each corn/callus; let dry use cushions with hole centered over corn or callus to relieve pressure (additional cushions may be purchased separately) repeat this procedure once or twice daily as needed for up to 14 days (until corn/callus is removed)

No Recall
Chain Drug Marketing Association Inc.

Salicylic Acid | Chain Drug Marketing Association Inc.

wash affected area, may soak wart in warm water for 5 minutes dry area thoroughly apply small amount of wart remover with applicator to sufficiently cover each wart let dry and repeat this procedure once or twice daily until wart is removed for up to 12 weeks

No Recall
Harmon Store Inc.

Salicylic Acid | Harmon Store Inc.

wash affected area may soak wart in for 5 minutes dry area thoroughly remove cap from pen remove insert pin from the tip twist and click pen until wart remover gel is dispense onto the tip of the applicator. Initial use will require several rotations for the gel to load apply a small amount at a time with applicator to sufficiently cover each wart let dry repeat this procedure once or twice daily as needed (until wart is removed) for up to 12 weeks for storage ensure applicator is free of excess gel before placing the insert pin back into the tip

No Recall

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