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Sentinel Flavor Tabs

Sentinel Flavor Tabs Recall

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Side Effects & Adverse Reactions

Not for human use. Keep this and all drugs out of the reach of children.

Not for human use. Keep this and all drugs out of the reach of children.

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FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

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Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

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FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.

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Uses

SENTINEL Flavor Tabs are indicated for use in dogs and puppies, four weeks of age and older, and two pounds body weight or greater. SENTINEL Flavor Tabs are also indicated for the prevention of heartworm disease caused by Dirofilaria immitis, for the prevention and control of flea populations, the control of adult Ancylostoma caninum (hookworm), and the removal and control of adult Toxocara canis and Toxocara leonina (roundworm) and Trichuris vulpis (whipworm) infections.

Lufenuron controls flea populations by preventing the development of flea eggs and does not kill adult fleas. Concurrent use of adulticide product may be necessary for adequate control of adult fleas.

SENTINEL Flavor Tabs may be used con currently with CAPSTAR® (nitenpyram) Tablets to provide a Flea Management System that kills adult fleas and prevents flea eggs from hatching. Please see the Supplemental Veterinary Package Insert provided with this product for information about concurrent use of the two products,

Without concurrent use of an adulticide, adequate flea control may not be achieved in dogs that have repeated exposure to flea infested animals or environments.

In dogs and puppies, the concurrent use of SENTINEL Flavor Tabs and CAPSTAR Tablets is indicated to kill adult fleas and prevent eggs from hatching. The effects of SENTINEL Flavor tabs, which prevent and control flea populations, and CAPSTAR Tablets, which treat flea infestations are combined to provide a FLEA MANAGEMENT SYSTEM.

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History

There is currently no drug history available for this drug.

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Other Information

SENTINEL Flavor Tabs are available in four tablet sizes in color-coded packages for oral administration to dogs and puppies according to their weight. (See Dosage Section). Each tablet is formulated to provide a minimum of 0.23 mg/pound (0.5 mg/kg) of milbemycin oxime and 4.55 mg/pound (10 mg/kg) body weight of lufenuron.

Milbemycin oxime consists of the oxime derivatives of 5-didehydromilbemycins in the ratio of approximately 80% A4 (C32H45NO7, MW 555.71) and 20% A3 (C31H43NO7, MW 541.68). Milbemycin oxime is classified as a macrocyclic anthelmintic.

Lufenuron is a benozylphenylurea derivative with the following chemical composition: N-[2,5-dichloro-4-(1,1,2,3,3,3, – hexafluoropropoxy)-phenylaminocarbonyl]-2,6- difluorobenzamide (C17H8Cl2F8N2O3, MW 511.15). Benzozylphenylurea compounds, including lufenuron, are classified as insect development inhibitors (IDIs).

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Sentinel Flavor Tabs Manufacturers

  • Novartis Animal Health Us, Inc.
    Sentinel Flavor Tabs | Novartis Animal Health Us, Inc.
    No Recall

    Sentinel Flavor Tabs | Novartis Animal Health Us, Inc.

    Sentinel Flavor Tabs | Novartis Animal Health Us, Inc.

    SENTINEL Flavor Tabs are given orally, once a month, at the recommended minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime and 4.55 mg/lb (10 mg/kg) lufenuron.

    Dogs over 100 lbs are provided the appropriate combination of tablets.

    *Please see separate insert in this package for concurrent dosing of SENTINEL Flavor Tabs and CAPSTAR Tablets

    TO ENSURE ADEQUATE ABSORPTION, ALWAYS ADMINISTER SENTINEL Flavor Tabs TO DOGS IMMEDIATELY AFTER OR IN CONJUNCTION WITH A NORMAL MEAL. Recommended Dosage Schedule Body Weight Milbemycin Oxime Per Tablet Lufenuron Per Tablet 2 to 10 lbs. 2.3 mg 46.0 mg 11 to 25 lbs. 5.75 mg 115 mg 26 to 50 lbs. 11.5 mg 230 mg 51 to 100 lbs. 23.0 mg 460 mg

    SENTINEL Flavor Tabs are palatable and most dogs will consume the tablet when offered by the owner. As an alternative to direct dosing, the tablets can be hidden in food. Be certain the dog consumes the entire tablet or tablets. Administer SENTINEL Flavor Tabs to dogs immediately after or in conjunction with a normal meal. Food is essential for adequate absorption of lufenuron. Watch the dog closely following administration to be sure the entire dose have been consumed. If it is not entirely consumed, redose with the full recommended dose as soon as possible.

    SENTINEL Flavor Tabs must be administered monthly, preferably on the same date each month. Treatment with SENTINEL Flavor Tabs may begin at any time of year. In geographic areas where mosquitoes and fleas are seasonal, the treatment schedule should begin one month prior to the expected onset and should continue until the end of “mosquito and flea season.” In areas with year-round infestations, treatment should continue through the entire year without interruption.

    If a dose is missed and a 30-day interval between dosing is exceeded, administer SENTINEL Flavor Tabs immediately and resume the monthly dosing schedule. If SENTINEL Flavor Tabs replace daily diethylcarbamazine (DEC) for heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.

    The combination of SENTINEL Flavor Tabs and CAPSTAR Tablets should be administered according to the following schedule. Weigh your dog prior to administration to ensure proper dosage. Do not administer to dogs under 2 pounds.

    Recommended Dosage Schedule Body Weight Dose CAPSTAR Once or twice weekly* (Nitenpyram per tablet) SENTINEL Flavor Tabs once per month (Lufenuron per tablet) 2 to 10 lbs. One Tablet 11.4 46.0 mg 11 to 25 lbs. One Tablet 11.4 115 mg 26 to 50 lbs. One Tablet 57.0 230 mg 51 to 100 lbs. One Tablet 57.0 460 mg 101 to 125 lbs. One Tablet 57.0 **

    *If adult fleas are seen

    **Dogs over 100 lbs. are provided the appropriate combination of SENTINEL Flavor Tabs.

  • Novartis Animal Health Us, Inc.
    Sentinel Flavor Tabs | Novartis Animal Health Us, Inc.
    No Recall

    Sentinel Flavor Tabs | Novartis Animal Health Us, Inc.

    Sentinel Flavor Tabs | Novartis Animal Health Us, Inc.

    SENTINEL Flavor Tabs are given orally, once a month, at the recommended minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime and 4.55 mg/lb (10 mg/kg) lufenuron.

    Dogs over 100 lbs are provided the appropriate combination of tablets.

    *Please see separate insert in this package for concurrent dosing of SENTINEL Flavor Tabs and CAPSTAR Tablets

     TO ENSURE ADEQUATE ABSORPTION, ALWAYS ADMINISTER SENTINEL Flavor Tabs TO DOGS IMMEDIATELY AFTER OR IN CONJUNCTION WITH A NORMAL MEAL.  Recommended Dosage Schedule  Body Weight  Milbemycin Oxime Per Tablet  Lufenuron Per Tablet  2 to 10 lbs.  2.3 mg  46.0 mg  11 to 25 lbs.  5.75 mg  115 mg  26 to 50 lbs.  11.5 mg  230 mg  51 to 100 lbs.  23.0 mg  460 mg

    SENTINEL Flavor Tabs are palatable and most dogs will consume the tablet when offered by the owner. As an alternative to direct dosing, the tablets can be hidden in food. Be certain the dog consumes the entire tablet or tablets. Administer SENTINEL Flavor Tabs to dogs, immediately after or in conjunction with a normal meal. Food is essential for adequate absorption of lufenuron. Watch the dog closely following administration to be sure the entire dose has been consumed. If it is not entirely consumed, redose with the full recommended dose as soon as possible.

    SENTINEL Flavor Tabs must be administered monthly, preferably on the same date each month. Treatment with SENTINEL Flavor Tabs may begin at any time of year. In geographic areas where mosquitoes and fleas are seasonal, the treatment schedule should begin one month prior to the expected onset and should continue until the end of “mosquito and flea season.” In areas with year-round infestations, treatment should continue through the entire year without interruption.

    If a dose is missed and a 30-day interval between dosing is exceeded, administer SENTINEL Flavor Tabs immediately and resume the monthly dosing schedule. If SENTINEL Flavor Tabs replace daily diethylcarbamazine (DEC) for heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.

    The combination of SENTINEL Flavor Tabs and CAPSTAR Tablets should be administered according to the following schedule. Weigh your dog prior to administration to ensure proper dosage. Do not administer to dogs under 2 pounds or less than 4 weeks of age.

    TO ENSURE ADEQUATE ABSORPTION, ALWAYS ADMINISTER SENTINEL FLAVOR TABS TO DOGS IMMEDIATELY OR IN CONJUNCTION WITH A NORMAL MEAL
    (See package insert for SENTINEL Flavor Tabs for details).

     Recommended Dosage Schedule  Body Weight  Dose  CAPSTAR Once or twice weekly* (Nitenpyram per tablet)  SENTINEL Flavor Tabs once per month (Lufenuron per tablet)  2 to 10 lbs.  One Tablet  11.4  46.0 mg  11 to 25 lbs.  One Tablet  11.4  115 mg  26 to 50 lbs.  One Tablet  57.0  230 mg  51 to 100 lbs.  One Tablet  57.0  460 mg  101 to 125 lbs.  One Tablet  57.0  **

    *If adult fleas are seen

    **Dogs over 100 lbs. are provided the appropriate combination of SENTINEL Flavor Tabs.

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