Tolazil label

Tolazil

Tolazil Recall

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Side Effects & Adverse Reactions

Keep out of reach of children. Not for human use.

This drug is for use in horses only and not for use in food-producing animals.

Avoid contact with eyes, skin and mucous membranes. In case of eye contact flush with plenty of water. Exposed skin should be washed with soap and water. In case of accidental oral exposure or injection, seek emergency medical attention.

Users with cardiovascular disease (for example, hypertension or ischemic heart disease) should take special precautions to avoid accidental exposure to this product.

To report adverse reactions in users or to obtain a copy of the material safety data sheet for this product, call 1-800-932-5676.

FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.

Uses

TolazilTM should be used in horses when it is desirable to reverse the effects of sedation and analgesia caused by xylazine.

History

There is currently no drug history available for this drug.

Other Information

TolazilTM contains tolazoline hydrochloride with the chemical name 1H-lmidazole,4,5-dihydro-2-(phenylmethyl)-monohydrochloride. Tolazoline hydrochloride has a molecular weight of 196.68 and the molecular formula is C10H12N2•HCl. The structural formula is

Structural Formula

Each mL contains: tolazoline hydrochloride equivalent to 100 mg base activity, chlorobutanol 5.0 mg, tartaric acid 7.8 mg, sodium citrate dihydrate 7.8 mg and water for injection. The pH is adjusted with hydrochloric acid and sodium citrate.

Tolazil Manufacturers

  • Vetone
    Tolazil | Vetone
    No Recall

    Tolazil | Vetone

    Tolazil | Vetone

    The TolazilTM dose is 4.0 mg/kg body weight or 1.8 mg/lb (4 mL/100 kg or 4 mL/220 lb) to reverse the sedative effects of xylazine. The carefully calculated dose of TolazilTM should be given slowly by intravenous injection. Administration rate should approximate 1 mL/second.1,5

    The table demonstrates the correct injection volume based on body weight:

    Body Weight (kg) Body Weight (lb) TolazilTM Injection Volume 250 kg 550 lb 10 mL 500 kg 1100 lb 20 mL