Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.
There is currently no manufacturer warning information available for this drug.
U-cort®, (Hydrocortisone Acetate Cream USP, 1%) is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Hydrocortisone Acetate Cream USP, 1% is intended for topical administration. The active component is the corticosteroid hydrocortisone acetate, which has the chemical name pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11,17-dihydroxy-11β)-. It has the following structural formula:
Molecular Weight: 404.50 Molecular Formula: C23H32O6
Each gram of the cream contains: 10 mg Hydrocortisone Acetate, USP in a water-washable cream base containing carbomer 940, cetyl alcohol, edetate disodium, isopropyl myristate, isopropyl palmitate, perfume, polypropylene 26 oleate, propylene glycol, purified water, sodium lauryl ether, sodium metabisulfite, stearic acid, trolamine, urea (10%) and xanthan gum.